儿童心力衰竭过程中凝血功能变化及抗凝治疗  

Changes of coagulation function and anticoagulant therapy in children with heart failure

作　　者：孙慧超[1] 张蕾[1] Sun Huichao;Zhang Lei(Children′s Hospital of Chongqing Medical University Ministry of Education Key Laboratory of Child Development and Disorders National Clinical Research Center for Child Health and Disorders International Science and Technology Cooperation Base of Child Development and Critical Disorders Chongqing Key Laboratory of Pediatrics,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院心血管科,儿童发育疾病研究教育部重点实验室,国家儿童健康与疾病临床医学研究中心,儿童发育重大疾病国家国际科技合作基地,儿科学重庆市重点实验室,重庆400014

出　　处：《中国小儿急救医学》2023年第1期25-30,共6页Chinese Pediatric Emergency Medicine

基　　金：中华心血管病发展专项基金(Z-2019-42-1908-2)。

摘　　要：血栓形成是心力衰竭的常见并发症,严重影响心力衰竭患者的生活质量。目前儿童心力衰竭的抗凝治疗仍不够规范,抗凝剂的使用也更多地依赖成人的用药经验,但儿童心力衰竭的病因和凝血系统发育与成人不同,抗凝治疗策略可能有所不同。本文就儿童心力衰竭过程中凝血功能改变及抗凝治疗做一介绍,以期对儿童慢性心力衰竭患者凝血系统管理及抗凝治疗提供参考。Thrombosis is a common complication of heart failure,which seriously affects the life quality of patients.At present,anticoagulant therapy in children with heart failure is still not standardized,and the use of anticoagulants depends more on the experience from adults.However,the etiology and coagulation system development of children are different from those of adults.So the anticoagulant treatment strategy for children with heart failure may be different.This review introduced the changes of coagulation function and anticoagulation therapy in children with heart failure,in order to provide reference for the management of coagulation system and anticoagulation therapy in children with chronic heart failure.

关 键 词：心力衰竭 儿童 抗凝治疗 

分 类 号：R725.4[医药卫生—儿科]