三维多孔碳材料的制备及对左氧氟沙星吸附性能研究  

A study on the synthesis performance of three-dimensional porous carbon materials and its adsorption performance on levofloxacin

作　　者：丁绮 李艳[1] 陈伟[1] 程辉[1] DING Qi;LI Yan;CHEN Wei;CHENG Hui(Shangluo Central Hospital,Shannxi 726000,China)

机构地区：[1]商洛市中心医院,陕西726000

出　　处：《中国卫生检验杂志》2023年第2期154-159,163,共7页Chinese Journal of Health Laboratory Technology

基　　金：商洛市科技计划(SK2019-65)。

摘　　要：目的 左氧氟沙星是临床上普遍使用的第三代氟喹诺酮类抗生素药物,其代谢物、残余药液排放到环境中会造成环境污染。方法 本文采用改进Hummer法制备了氧化石墨烯,进一步利用低温煅烧技术制备了大比表面的三维多孔碳材料,在200℃马弗炉中煅烧2 min,比表面积可达到675.62 m^(2)/g。通过等温吸附实验研究其对左氧氟沙星的吸附机理和效果。结果 三维多孔碳材料在pH值为4~7内对左氧氟沙星表现出优异的吸附性能。通过优化实验条件,当三维多孔碳材料的投加量为20 mg,对100 ml 30 mg/L的左氧氟沙星在pH值=5时吸附量可达到115.63 mg/g。准二级动力学方程跟Langmuir方程能很好地描述三维多孔碳材料的吸附,对其吸附热力学数据进行分析表明三维多孔碳材料对左氧氟沙星的吸附是一个自发、吸热、无序的过程。结论 低温煅烧制备的三维多孔碳材料是一种潜在性能优良的抗生素吸附材料。Objective Levofloxacin is the third generation of fluoroquinolone antibiotics widely used in clinical practice. Its metabolites and residual liquid are discharged into the environment, causing environmental pollution. Methods In this paper, graphene oxide was prepared by the modified Hummer method, and three-dimensional porous carbon material with large specific surface was prepared by low temperature calcination technology. The specific surface area reached 675.62 m^(2)/g when calcined in a Muffle furnace at 200 ℃ for 2 min. The adsorption mechanism and effect of levofloxacin were studied by isothermal adsorption experiments. Results The three-dimensional porous carbon material showed excellent adsorption performance for levofloxacin in the pH range of 4-7. By optimizing the experimental conditions, when the dosage of three-dimensional porous carbon material is 20 mg, the adsorption capacity of three-dimensional porous carbon material to 100 ml 30 mg/L levofloxacin can reach 115.63 mg/g at pH=5. The quasi-secondary kinetic equation and the Langmuir equation can describe the adsorption process of the three-dimensional porous carbon material. Furthermore, the adsorption thermodynamic analysis showed that the adsorption of levofloxacin by three-dimensional porous carbon material was a spontaneous, endothermic, and disordered process. Conclusion The results show that the three-dimensional porous carbon material prepared by low temperature calcination is a potential antibiotic adsorption material with excellent performance.

关 键 词：左氧氟沙星 三维多孔碳材料 氧化石墨烯 吸附 低温煅烧 

分 类 号：R446[医药卫生—诊断学]