肥胖和中心性肥胖高血压控制不良患者合并血脂异常、糖尿病和高尿酸血症的分析  

Analysis of dyslipidemia, diabetes and hyperuricemia in obesity and central obesity patients with poorly controlled hypertension

作　　者：沈益妹[1] 章奇 俞梅华[1] 丁晶莹[1] 朱新凤[1] SHEN Yi-mei;ZHANG Qi;YU Mei-hua;DING Jing-ying;ZHU Xin-feng(Huzhou Municipal Center for Disease Control and Prevention,Zhejiang 313000,China)

机构地区：[1]湖州市疾病预防控制中心,浙江313000

出　　处：《中国卫生检验杂志》2023年第3期327-331,共5页Chinese Journal of Health Laboratory Technology

基　　金：2021年湖州市科技局公益性应用研究医卫一般项目(2021GYB67)。

摘　　要：目的 研究肥胖与中心性肥胖高血压控制不良患者合并血脂异常、糖尿病与高尿酸血症的情况。方法 采用多阶段分层整群抽样方法,对1 215例患者进行问卷调查、体格检查和实验室检测,比较肥胖、中心性肥胖与非肥胖患者的血压水平,血脂异常、糖尿病与高尿酸血症患病率差异。结果 肥胖与中心性肥胖患者的舒张压水平高于体质量指数正常/体质量指数偏低患者(P<0.05),其血压值随着年龄的增长而降低(P<0.05)。合并血脂异常患病率为45.10%,其中合并低HDL-C血症患病率男性高于女性、合并高TC血症患病率女性高于男性(P<0.05)。合并高尿酸血症、糖尿病单病种或糖尿病与血脂异常2个病种的患病率分别为23.05%、30.95%、60.58%。结论 湖州市肥胖与中心性肥胖的高血压控制不良患者同时合并血脂异常与糖尿病的患病率高,其血脂异常特点为TG升高、HDL-C降低。Objective This paper aims to study the prevalence of dyslipidemia, diabetes and hyperuricemia in obesity and central obesity patients with poorly controlled hypertension. Methods A multi-stage stratified cluster sampling method was used to conduct a questionnaire survey, physical examination and laboratory test on 1 215 patients. The blood pressure levels, prevalence of dyslipidemia, diabetes and hyperuricemia were compared among obese, central obesity and non-obese patients. Results The diastolic blood pressure of obesity and central obesity patients was higher than that of normal weight/low weight patients(P<0.05), and its value decreased with age(P<0.05). The prevalence of dyslipidemia was 45.10%. The prevalence of low HDL-C in males was higher than that in females, and the prevalence rate of high TC in females was higher than that in males(P<0.05). The prevalence rates of hyperuricemia, diabetes alone or diabetes with dyslipidemia were 23.05%, 30.95% and 60.58%, respectively. Conclusion The prevalence of dyslipidemia and diabetes is high in obesity and central obesity patients with poor hypertension control in Huzhou City. The dyslipidemia is characterized by increased TG and decreased HDL-C.

关 键 词：高血压 肥胖与中心性肥胖 血脂异常 糖尿病 患病率 

分 类 号：R589[医药卫生—内分泌]