四种昼间啮齿类动物的活动模式及其应用进展  

Locomotor activity of four diurnal rodents and their applications

作　　者：邢亦谦 高泓[1] 谢红艳[1] 谢春光[1] XING Yiqian;GAO Hong;XIE Hongyan;XIE Chunguang(TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Chengdu University of Traditional Chinese Medicine,Chengdu 610075)

机构地区：[1]成都中医药大学附属医院,代谢性疾病中医药调控四川省重点实验室,成都610075 [2]成都中医药大学,成都610075

出　　处：《中国实验动物学报》2022年第8期1095-1101,共7页Acta Laboratorium Animalis Scientia Sinica

基　　金：国家自然科学基金(82004354);国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202209);岐黄学者项目。

摘　　要：昼间啮齿类动物具有与人类相似的昼夜节律,随着生物钟的发现,近年来此类动物逐渐展露出夜间啮齿类动物所不能替代的优势,以新兴模型的姿态出现在代谢、光反应、神经调节、社会行为等医学研究领域。然而国内尚缺乏此类动物的报道。因此,本文回顾昼间动物时间生态位的调控,着重介绍长爪沙鼠(Meriones unguiculatus)、智利八齿鼠(Octodon degus)、尼罗河草鼠(Arvicanthis niloticus)和羚羊地松鼠(Ammospermophilus leucurus)这四种较公认的昼间啮齿类动物的活动模式和应用进展,以期为时间生物学研究提供有力工具。Diurnal rodents and humans share similar circadian rhythms.Since the discovery of the circadian clock,scientists have gradually recognized that diurnal rodents exhibit irreplaceable advantages over nocturnal rodents.Recently,they have been exploited as novel models in medical fields such as metabolism,light reflection,neurology regulation,and social behavior.However,diurnal rodents are poorly understood in China.In this paper,we discuss the evolution of circadian rhythms in diurnal animals and the mechanisms behind these animals’temporal niches.Moreover,to provide an information source for chronobiology,the locomotor activity and application of four well-defined diurnal rodents,Meriones unguiculatus,Octodon degus,Arvicanthis niloticus,and Ammospermophilus leucurus,are reviewed.

关 键 词：昼间啮齿类动物 昼夜节律 活动模式 动物模型 

分 类 号：Q95-33[生物学—动物学]