2008-2021年南充市手足口病流行特征分析  

Epidemiological characteristics of hand-foot-mouth disease in Nanchong City from 2008 to 2021

作　　者：杨帆[1] 甘霖[1] 敬维[1] 苟铁军[1] 张明洪[1] 青承昀[2] YANG Fan;GAN Lin;JING Wei;GOU Tiejun;ZHANG Minghong;QING Chengyun(Nanchong Center for Disease Control and Prevention,Nanchong 637000,Sichuan Province,China;Gaoping Center for Disease Control and Prevention,Nanchong 637100,Sichuan Province,China)

机构地区：[1]南充市疾病预防控制中心,四川南充637000 [2]南充市高坪区疾病预防控制中心,四川南充637100

出　　处：《预防医学情报杂志》2023年第2期128-132,139,共6页Journal of Preventive Medicine Information

摘　　要：目的 分析南充市2008—2021年手足口病流行病学及病原学特征,为预防和控制南充市手足口病疫情提供科学依据。方法 采用描述流行病学方法对南充市2008—2021手足口病疫情资料进行统计分析。采用Excel 2019软件对数据进行统计,采用SPSS 23.0软件对数据进行分析,以P<0.05为差异有统计学意义。结果 2008—2021年南充市共报告手足口病病例46 094例,年均报告发病率为51.81/10万,各年度报告发病率差异有统计学意义(χ^(2)=1 716.88,P<0.001)。各月均有手足口病病例报告,整体疫情4—7月(18 586例)和10—12月(16 860)报告病例数较多,各月之间报告发病率差异有统计学意义(χ^(2)=9324.41,P<0.001)。年均发病率前3位的地区是阆中市(69.63/10万)、仪陇县(67.88/10万)、西充县(64.45/10万),各区、县年均报告发病率差异有统计学意义(χ^(2)=3 919.45,P<0.001)。发病率男性高于女性,差异有统计学意义(χ^(2)=1 280.48,P<0.001);报告病例年龄主要集中在0~5岁年龄组(43 968例)占报告病例总数的95.39%,各年龄组年均报告发病率差异有统计学意义(χ^(2)=858 557.42,P<0.001);病例分布于15个人群类别,居前3位的是散居儿童33 027例(71.65%),幼托儿童11 264例(24.44%),学生1 544例(3.35%)。病原学分型构成为:其他肠道病毒1 610例(54.52%)、EV 71型717例(40.43%),Cox A16型626例(21.20%)。结论 南充市2008—2021手足口病报告发病率趋势变化基本呈偶数年份较高,奇数年份较低;发病时间具有春夏季及秋冬流行特点;阆中市、仪陇县和西充县年均发病率较高;发病率男性高于女性,发病人群集中在0~5岁年龄组,人群类别以散居儿童、幼托儿童和学生为主;病原学构成以其他肠道病毒病为主。Objective To analyze the epidemiological characteristics of hand-foot-mouth disease(HFMD) in Nanchong City from 2008 to 2021,and to provide scientific basis for the prevention and control of HFMD in Nanchong City.Methods Descriptive epidemiological methods were used to conduct statistical analysis on the epidemic data of HFMD in Nanchong City from 2008 to 2021.Excel2019 and SPSS 23.0 were used to analyze the data,and P<0.05 was considered as statistically significant.Results From 2008 to 2021,a total of 46 094 cases of HFMD were reported in Nanchong,with an average annual reported incidence rate of 51.81/105.The difference of the annual reported incidence rate of different years was statistically significant (χ^(2)=1 716.88,P<0.001).HFMD cases were reported in all months.There were large numbers of cases reported from April to July(18 586cases) and from October to December(16 860).And there were statistically significant differences in the reported incidence rate among all months (χ^(2)=9 324.41,P<0.001).The top three regions with higher average annual incidence rates were Langzhong City(69.63/105),Yilong County(67.88/105) and Xichong County(64.45/105).The difference of average annual reported incidence rate among districts and counties was statistically significant (χ^(2)=3 919.45,P<0.001).The incidence rate in men was higher than that in women,and the difference was statistically significant (χ^(2)=1 280.48,P<0.001).The age of reported cases was mainly concentrated in the 0-5 years old group(43 968cases),accounting for 95.39% of the total number of reported cases.The difference in the average annual reported incidence rate among different age groups was statistically significant (χ^(2)=858 557.42,P<0.001).The cases were distributed in 15 population groups.The top three were scattered children(33 027 cases,71.65%),childcare children(11 264 cases,24.44%) and students(1 544cases,3.35%).The composition of pathogenic subtypes were other enterovirus(1 610 cases,54.52%),EV 71(717 cases,40.43%) and Cox A16(626 cas

关 键 词：手足口病 流行特征 发病率 病原学 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]