Proteomic Analysis Revealed the Involvement of Autophagy in Rat Acute Lung Injuries Caused by Gas Explosion Based on a Data-Independent Acquisition Strategy  

作　　者：HONG Shan DING Chun Jie ZHOU Qiang SUN Yun Zhe ZHANG Miao LI Ning DONG Xin Wen GUAN Yi ZHANG Lin TIAN Lin Qiang CAO Jia YAO Wu REN Wen Jie YAO San Qiao 

机构地区：[1]School of Public Health,Xinxiang Medical University,Xinxiang 453003,Henan,China [2]Department of Nephrology,Xinxiang Second People’s Hospital,Xinxiang 453003,Henan,China [3]School of Public Health,North China University ofScience and Technology,Tangshan 063210,Hebei,China [4]Clinical Medical Research Center for Women and ChildrenDiseases,Maternal and Child Health Care Hospital of Shandong Province,Shandong University,Jinan 250001,Shandong,China [5]Institute of Trauma and Orthopedics,Xinxiang Medical University,Xinxiang 453003,Henan,China [6]ToxicologyResearch Institute,PLA Army Medical University,Chongqing 400038,China [7]School of Public Health,ZhengzhouUniversity,Zhengzhou 450000,Henan,China

出　　处：《Biomedical and Environmental Sciences》2023年第2期206-212,共7页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China[grant numbers U1904209 andU2004102];the Open Project of the Third Affiliated Hospital of Xinxiang Medical University[fund number.KFKTZD202101];the Graduate Research Innovation Support Program of Xinxiang Medical University[grant Number.YJSCX202157Y].

摘　　要：Gas explosion injury is a compound injury caused by a shock wave,high-temperature flame,or toxic gas directly or indirectly acting on the human body,resulting in multiple organ damage.As a hyperaerated tissue,the lung is the primary organ that experiences an early injury.The pathological manifestations of gas-explosion-induced acute lung injury(ALI)include pulmonary tissue edema.

关 键 词：LUNG LUNG ACUTE 

分 类 号：R563.8[医药卫生—呼吸系统]