弹性成像技术在非酒精性脂肪性肝病肝纤维化无创诊断中的应用进展  

Advances in the application of elastography in noninvasive diagnosis of liver fibrosis in nonalcoholic fatty liver disease

作　　者：陆梦 王铭杰[1] 陈立[1] LU Meng;WANG Mingjie;CHEN Li(Department of Gastroenterology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 201801,China)

机构地区：[1]上海交通大学医学院附属瑞金医院消化内科,上海201801

出　　处：《临床肝胆病杂志》2023年第2期408-412,共5页Journal of Clinical Hepatology

基　　金：上海市科技创新行动计划扬帆计划(21YF1440400)。

摘　　要：非酒精性脂肪性肝病(NAFLD)已成为最常见的慢性肝病,肝纤维化与NAFLD的预后密切相关,精准评估肝纤维化至关重要。NAFLD诊断的金标准是肝穿刺活检,然而其有创性限制了临床应用。基于超声和磁共振的弹性成像技术逐渐应用于NAFLD相关纤维化诊断中,本文主要介绍两项技术的原理,比较各自优缺点以及结合人工智能技术的应用进展。Nonalcoholic fatty liver disease(NAFLD) has become the most common chronic liver disease,and liver fibrosis is closely associated with the prognosis in NAFLD;therefore,accurate assessment of liver fibrosis is of great importance.Liver biopsy is the gold standard for the diagnosis of NAFLD,but its clinical application is limited by invasiveness.Elastography technique based on ultrasound and magnetic resonance imaging has gradually been applied in the diagnosis of liver fibrosis associated with NAFLD.This article elaborates on the principles of the two techniques,compares their respective advantages and disadvantages,and introduces the advances in application in combination with artificial intelligence.

关 键 词：弹性成像技术 非酒精性脂肪性肝病 肝硬化 诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学] R575[医药卫生—诊断学]