基于智能纤维和纺织品的可穿戴生物传感器  

Wearable Biosensors Based on Smart Fibers and Textiles

作　　者：孙华悦 向宪昕 颜廷义 曲丽君[1,2] 张光耀 张学记 Huayue Sun;Xianxin Xiang;Tingyi Yan;Lijun Qu;Guangyao Zhang;Xueji Zhang(Research Center for Intelligent and Wearable Technology,College of Textiles and Clothing,Qingdao University,Qingdao 266071,China;State Key Laboratory of Bio-Fibers and Eco-Textiles,Qingdao University,Qingdao 266071,China;School of Biomedical Engineering,Shenzhen University,Shenzhen 518060,China)

机构地区：[1]青岛大学纺织服装学院智能可穿戴技术研究中心,青岛266071 [2]青岛大学省部共建生物多糖纤维成形与生态纺织国家重点实验室,青岛266071 [3]深圳大学生物医学工程学院,深圳518060

出　　处：《化学进展》2022年第12期2604-2618,共15页Progress in Chemistry

基　　金：国家自然科学基金项目(Nos.22204089,21890742);山东省自然科学基金项目(No.ZR2020QB092);中国博士后科学基金项目(No.2021M691689);青岛市博士后应用研究项目(No.202142);省部共建生物多糖纤维成形与生态纺织国家重点实验室自主课题项目(Nos.ZKT23,GZRC202025)。

摘　　要：随着社会经济发展,人们越来越重视身体健康,对医疗设备的智能化、便携性、准确性要求越来越高。在此背景下,可穿戴生物传感器的市场需求不断提升。智能纤维和纺织品能够满足透气性和可穿戴性的要求,应用在可穿戴生物传感器中能够实时监测人们的身体状况,包括脉搏、呼吸、肢体运动等生命体征监测,汗液、唾液等成分分析和呼出物的检测。相比于传统的生物传感器,基于智能纤维和纺织品的可穿戴生物传感器可用于现场即时监测,从疾病预防、改善临床结果和生活质量到提高生产力、减轻医疗负担和降低医疗成本都发挥着重要作用。在这里,本文主要介绍了近几年智能纤维和纺织品在可穿戴生物传感器中的应用,按照生命体征监测、体液分析和呼出物检测这三个方面,对其传感策略例如比色传感、荧光传感、压电式传感等进行介绍。最后,我们对智能纤维与纺织品在可穿戴生物传感器中的应用状况以及面临的问题进行总结,并对其在可穿戴生物传感器的未来发展进行展望。With the development of social economy,people pay more and more attention to physical health and demand more and more intelligence,portability and accuracy of medical devices,in this context,the market demand for wearable biosensors is rising.Smart fibers and textiles can meet the requirements of air permeability and wearability,and can be used in wearable biosensors to monitor people’s physical condition in real time.For vital signs monitoring,they can be used to reflect physiological status such as heartbeat,pulse,respiration and body movements in real time.For body fluid detection,the components in sweat,tears and saliva can be analyzed in real time.They can also analyze the exhaled products.Using the characteristics of wearing the sensor on the body,people can monitor their health while living and working normally.Compared with traditional biosensors,wearable biosensors based on smart fibers and textiles can be used for on-site real-time monitoring,and play an important role in preventing diseases,improving clinical outcomes and quality of life,increasing productivity,reducing medical burden and reducing medical costs.Here,this review mainly introduces the application of smart fibers and textiles in wearable biosensors in recent years,and according to three aspects(vital signs monitoring,body fluids detection and exhaled products detection),we introduce their sensing strategies such as colorimetric sensing,fluorescence sensing,piezoelectric sensing,etc.Finally,we summarize the application status and problems of smart fibers and textiles in wearable biosensors,and look forward to their future development.

关 键 词：智能纤维和纺织品 可穿戴生物传感器 生命体征 体液 呼出物 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] R318[自动化与计算机技术—控制科学与工程]