高原急性呼吸窘迫综合征诊断相关研究进展  

Research progress on diagnosis of high-altitude acute respiratory distress syndrome

作　　者：郭利涛[1] 张万奎 马四清[3] Guo Litao;Zhang Wankui;Ma Siqing(Department of Critical Care Medicine,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Department of Critical Care Medicine,the First People's Hospital of Haidong,Qinghai Province,Haidong 810699,China;Department of Critical Care Medicine,Qinghai Provincial People's Hospital,Xining 810007,China)

机构地区：[1]西安交通大学第一附属医院重症医学科,西安710061 [2]青海省海东市第一人民医院重症医学科,海东810699 [3]青海省人民医院重症医学科,西宁810007

出　　处：《中国医药》2023年第3期434-438,共5页China Medicine

基　　金：青海省重点研发与转化计划(2019-SF-132)。

摘　　要：急性呼吸窘迫综合征(ARDS)是常见的呼吸系统危重症,发病率和死亡率都很高。高原气压低、氧含量低、干燥寒冷、强辐射及气候多变的环境对人体健康有巨大的影响。高海拔地区急慢性缺氧可诱发多种疾病,ARDS的发病率也显著增加,为16.70%~20.72%。低氧是高原ARDS的诱发及加重因素。高原ARDS尽管与平原地区的ARDS有许多相似之处,但高原低压低氧的环境,造成高原ARDS独特的病理生理特征,因此其诊断标准和低海拔地区不完全相同。海拔氧合指数校正的柏林标准可以区分高原ARDS的严重程度,但仍存在争议,对于高原ARDS诊断目前仍没有统一可行的标准。本文就高原ARDS诊断方面的相关研究进展进行综述。Acute respiratory distress syndrome(ARDS)is a common respiratory disease with high morbidity and mortality.The plateau environment of low pressure,low oxygen,dry,cold,strong radiation and changeable climate have a huge impact on human health.Acute and chronic hypoxia at high-altitudes may induce a variety of diseases.The incidence of ARDS also increases significantly,nearly 16.70%-20.72%.Hypoxia is an inducing and aggravating factor of high-altitude ARDS.Although high-altitude ARDS has many similarities with plains ARDS,the high-altitude hypobaric and hypoxic environment results in unique pathophysiological characteristics of high-altitude ARDS,so its diagnostic criteria are not exactly the same as those in low-altitude areas.The oxygenation index altitude-adjusted Berlin criteria correctly identified the severity of high-altitude ARDS,however,the diagnostic criteria for high-altitude ARDS is still controversial.There is still no uniform and feasible standard for the diagnosis of high-altitude ARDS.This paper reviews the research progress on the diagnosis of high-altitude ARDS.

关 键 词：急性呼吸窘迫综合征 高原肺水肿 高原疾病 诊断 

分 类 号：R825.6[医药卫生—临床医学]