音乐治疗对维持性血液透析患者抑郁和焦虑状态影响的随机对照研究  

Effect of music therapy on depression and anxiety in patients with maintenance hemodialysis:a randomized controlled study

作　　者：王婷婷 张晓颖[2] 戴珊珊[1] 王欣欣[1] 于海艳[1] 马迎春[1] Wang Tingting;Zhang Xiaoying;Dai Shanshan;Wang Xinxin;Yu Haiyan;Ma Yingchun(Department of Nephrology,Beijing Boai Hospital,China Rehabilitation Research Center,Rehabilitation Medical College,Capital Medical University,Beijing 100068,China;Department of Psychological Music Therapy Center,Beijing Boai Hospital,China Rehabilitation Research Center,Rehabilitation Medical College,Capital Medical University,Beijing 100068,China)

机构地区：[1]首都医科大学康复医学院,中国康复研究中心北京博爱医院肾内科,北京100068 [2]首都医科大学康复医学院,中国康复研究中心北京博爱医院心理科音乐治疗中心,北京100068

出　　处：《中华肾脏病杂志》2022年第12期1048-1054,共7页Chinese Journal of Nephrology

基　　金：中国康复研究中心青年基金(2020-Q7)。

摘　　要：目的探讨音乐治疗对维持性血液透析(maintenance hemodialysis,MHD)患者抑郁和焦虑状态的影响。方法该研究为单中心开放性随机对照研究。选择2021年3月1日至2021年4月24日中国康复研究中心规律血液透析≥3个月且贝克抑郁量表(Beck depression inventory,BDI)评分≥10分的MHD患者,采用随机信封法将其分为音乐组与对照组。音乐治疗方案由音乐治疗师选取治疗乐曲、建立预定曲目库,乐曲总时间长约2 h。音乐组在常规血液透析治疗期间同时接受每周3次、每次1.0~1.5 h的聆听式音乐治疗,对照组仅接受常规血液透析治疗,所有入组患者完成为期8周的治疗。使用BDI及状态-特质焦虑量表(state-trait anxiety inventory,STAI)评估MHD患者治疗前后的心理状态。结果共入组MHD患者64例,年龄(59.19±11.61)岁,其中男性38例(59.38%)。音乐组32例,对照组32例。音乐组组内比较BDI评分[治疗2周(9.81±6.25)分,治疗8周(8.30±8.49)分,F=49.75,P<0.001]和STAI评分[治疗2周(49.30±7.27)分,治疗8周(47.07±7.39)分,F=13.09,P<0.001]在治疗2周时即可出现明显下降且能稳定持续8周;治疗后,音乐组BDI评分显著低于对照组[治疗2周(9.81±6.25)分比(14.13±7.33)分,t=-2.53,P=0.014;治疗8周(8.30±8.49)分比(12.56±5.67)分,t=-2.34,P=0.023],STAI评分显著低于对照组[治疗2周(49.30±7.27)分比(54.00±8.36)分,t=-2.06,P=0.043;治疗8周(47.07±7.39)分比(51.34±8.87)分,t=-2.06,P=0.044]。结论音乐治疗可以快速、有效改善MHD患者的抑郁和焦虑状态。Objective To investigate the effect of music therapy on depression and anxiety status in maintenance hemodialysis(MHD)patients.Methods The study was a single⁃center,open,and randomized controlled trial.The patients with regular hemodialysis of more than 3 months and the Beck depression inventory(BDI)scores≥10 in China Rehabilitation Research Center from March 1 to April 24,2021 were selected.Random envelope method was used to divide the enrolled patients into music group and control group.The music therapist selected the treatment music and established the preset repertoire library in the music therapy programs,and the total duration of music was about 2 hours.The music group received listening music therapy of 1.0 to 1.5 hours 3 times a week during routine hemodialysis treatment,while the control group only received routine hemodialysis treatment.All the enrolled patients completed treatment of 8 weeks.The BDI and state⁃trait anxiety inventory(STAI)were used to assess the psychological status of MHD patients before and after treatment.Results A total of 64 MHD patients were enrolled,aged(59.19±11.61)years old,among whom 38 patients(59.38%)were males.There were 32 patients in the music group and 32 patients in the control group.BDI scores[2 weeks(9.81±6.25)scores,8 weeks(8.30±8.49)scores,F=49.75,P<0.001]and STAI scores[2 weeks(49.30±7.27)scores,8 weeks(47.07±7.39)scores,F=13.09,P<0.001]in the music group decreased significantly after 2 weeks of treatment and remained stable for 8 weeks.After treatment,the BDI scores in the music group were significantly lower than those in the control group[2 weeks(9.81±6.25)scores vs(14.13±7.33)scores,t=-2.53,P=0.014;8 weeks(8.30±8.49)scores vs(12.56±5.67)scores,t=-2.34,P=0.023],and STAI scores in the music group were significantly lower than those in the control group[2 weeks(49.30±7.27)scores vs(54.00±8.36)scores,t=-2.06,P=0.043;8 weeks(47.07±7.39)scores vs(51.34±8.87)scores,t=-2.06,P=0.044].Conclusion Music therapy can improve depression and anxiety of MHD

关 键 词：肾透析 抑郁 焦虑 音乐治疗 随机对照试验 

分 类 号：R692.5[医药卫生—泌尿科学]