电化学促进的烯烃和炔烃双官能团化反应研究进展  

Recent Progress on the Electrochemical Difunctionalization of Alkenes/Alkynes

作　　者：李秀英[1] 陶萍芳[1] 程泳渝 胡琼 黄伟娟 李芸[1] 罗志辉[1] 黄国保[1] Li Xiuying;Tao Pingfang;Cheng Yongyu;Hu Qiong;Huang Weijuan;Li Yun;Luo Zhihui;Huang Guobao(Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology,Yulin Normal University,Yulin,Guangxi 537000)

机构地区：[1]玉林师范学院、广西农产资源化学与生物技术重点实验室,广西玉林537000

出　　处：《有机化学》2022年第12期4169-4201,共33页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21961042);广西高校中青年教师基础能力提升(Nos.2021KY0587,2022KY0572);玉林师范学院科研(Nos.G2021ZK16,G2022ZK08)资助项目。

摘　　要：不饱和烃(烯烃或炔烃)的双官能团化反应是引入一些官能团的重要策略,也是合成多取代烃类化合物的重要方法,在天然产物全合成及药物合成等领域被广泛应用.综述了最近五年来电化学介导不饱和烃的双官能团化反应中的最新研究进展.按照烯烃的双官能团化、不饱和烃的环化反应的分类介绍了电化学介导在不饱和烃的双官能团化反应中的应用及相关的反应机理,为今后此类反应在有机合成中的应用提供参考.The difunctionalization of unsaturated hydrocarbons(alkenes or alkynes)is an important strategy to introduce functional groups,and is also an important method to synthesize polysubstituted hydrocarbons,which is widely used in the fields of total synthesis of natural products and drug synthesis.The latest research progress on the electrochemically enabled difunctionalization of alkenes or alkynes in recent five years is summarized.According to the classification of difunctionalization of alkenes and cyclization of unsaturated hydrocarbon,the application and the related reaction mechanism are introduced.It is hoped that this review can be referred to the future application in organic synthesis of electrochemicmediated difunctionalization of alkenes/alkynes.

关 键 词：电化学 烯烃/炔烃 双官能团化 

分 类 号：O621.25[理学—有机化学]