碘化钾介导的电催化N-酰基/磺酰基次磺酰胺的合成  

Electrochemical Synthesis of N-Acyl/Sulfonylsulfenamides Using Potassium Iodide as Mediator

作　　者：魏兆鑫 王仁杰 张永红[1] 王斌[1] 夏昱 金伟伟 刘晨江[1] Wei Zhaoxin;Wang Renjie;Zhang Yonghong;Wang Bin;Xia Yu;Jin Weiwei;Liu Chenjiang(College of Chemistry,Xinjiang University,Urumqi 830017)

机构地区：[1]新疆大学化学学院,乌鲁木齐830017

出　　处：《有机化学》2022年第11期3730-3739,共10页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21702175,21961037,22161044);新疆维吾尔自治区天山创新团队(No.2021D14011);新疆维吾尔自治区自然科学基金(No.2020D01C077)资助项目.

摘　　要：开发了一种高效、环保的电催化方法合成N-酰基/磺酰基取代的次磺酰胺类化合物.在单室电解池中,不同取代基取代的缺电子胺和芳基硫醇反应良好,以36%~98%的收率得到N—S键偶联产物.初步的机理研究表明,该反应可能通过自由基过程进行.An efficient and environmentally friendly electrocatalytic protocol has been developed for synthesizing N-acyl/sulfonyl sulfenamides.In an undivided cell,various electron-deficient groups substituted amines and aryl thiols react smoothly to afford the N—S bond formation products in 36%~98%yields.Preliminary mechanistic studies indicate that the reaction may work through a free radical process.

关 键 词：电合成 N—S键构建 次磺酰胺 交叉偶联放氢反应 

分 类 号：O621.251[理学—有机化学]