光电协同技术联合中药面膜治疗轻中度玫瑰痤疮的疗效及安全性分析  

Efficacy and safety of electro-optical synergy technology combined with traditional Chinese medicine facial mask in treating mild to moderate acne rosacea

作　　者：王璐 王永琴 毛颖 张伟 张蕊 Wang Lu;Wang Yong-qin;Mao Ying;Zhang Wei;Zhang Rui(Department of Dermatology,The Second Affiliated Hospital of Qiqihar Medical University,Qiqihar,Heilongjiang 161006,China;Department of Clinical Pharmacy,The Second Affiliated Hospital of Qiqihar Medical University,Qiqihar,Heilongjiang 161006,China;Department of Traditional Chinese Medicine,The Second Affiliated Hospital of Qiqihar Medical University,Qiqihar,Heilongjiang 161006,China)

机构地区：[1]齐齐哈尔医学院附属第二医院皮肤科,黑龙江齐齐哈尔161006 [2]齐齐哈尔医学院附属第二医院临床药学,黑龙江齐齐哈尔161006 [3]齐齐哈尔医学院附属第二医院中医科,黑龙江齐齐哈尔161006

出　　处：《中国现代医学杂志》2023年第4期62-65,共4页China Journal of Modern Medicine

基　　金：黑龙江省省属高等学校基本科研项目(No:2020-KYYWF-0028);齐齐哈尔市科学技术计划项目(No:SFZD-2019164)。

摘　　要：目的探究光电协同技术联合中药面膜治疗轻中度玫瑰痤疮的疗效及安全性。方法选取2021年3月—2022年1月齐齐哈尔医学院附属第二医院收治的68例玫瑰痤疮患者作为研究对象。将患者随机分为研究组和对照组,各34例。对照组予以光电协同技术治疗,研究组在对照组基础上联合中药面膜治疗,两组均于治疗9周后评估临床疗效、中医证候积分、面部功能、情绪,并记录治疗期间不良反应发生情况。结果研究组临床疗效优于对照组(P<0.05)。研究组治疗前后主证、次证积分的差值高于对照组(P<0.05)。两组患者治疗前后pH值的差值比较,差异无统计学意义(P>0.05)。研究组治疗前后红斑量、角质层含水率、经皮水分流失量的差值高于对照组(P<0.05)。研究组治疗前后HAMA评分、HAMD评分的差值高于对照组(P<0.05)。两组患者不良反应率比较,差异无统计学意义(P>0.05)。结论中药面膜应用于轻中度玫瑰痤疮治疗中临床疗效好,可有效改善皮肤功能,安全性良好,有助于消除患者焦虑等负面情绪。Objective To explore the efficacy and safety of electro-optical synergy technology combined with traditional Chinese medicine facial mask in treating mild to moderate acne rosacea.Methods The 68 patients with acne rosacea treated in our hospital from March 2021 to January 2022 were selected and randomly divided into the study group and the control group,with 34 cases in each group.The control group was treated with the electrooptical synergy,while the study group was treated with Chinese medicine mask on the basis of the electro-optical synergy.The clinical efficacy,TCM syndrome scored,facial function and emotion of patients in the two groups were evaluated after 9 weeks of treatment.Adverse reactions during the treatment were recorded.Results The clinical efficacy of the study group was better than that of the control group(P<0.05).The differences of main and secondary syndrome scores before and after the treatment in the study group were higher than those in the control group(P<0.05).The difference of the pH value before and after the treatment was not different between the two groups(P>0.05).The differences of the erythema dose,the water content of the stratum corneum,and the transepidermal water loss before and after the treatment in the study group were higher than those in the control group(P<0.05).The differences of Hamilton Anxiety Rating Scale and Hamilton Depression Rating Scale scores before and after the treatment in the study group were higher than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Traditional Chinese medicine facial mask is effective in treating mild to moderate acne rosacea.It can effectively improve skin function with few safety concerns,and is beneficial for patients to get rid of anxiety and other negative emotions.

关 键 词：玫瑰痤疮 光电协同技术 中药面膜 安全性 情绪 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]