广州地区肺癌高危人群筛查依从性及筛查结果分析  

Screening compliance and screening results in high-risk populations of lung cancer in Guangzhou

作　　者：张耀森 卢国杰 钟惠铃 高建伟 ZHANG Yao-sen;LU Guo-jie;ZHONG Hui-ling;GAO Jian-wei(Guangzhou Panyu Central Hospital,Guangzhou 511400,China)

机构地区：[1]广州市番禺区中心医院,广东广州511400

出　　处：《华南预防医学》2022年第12期1455-1459,共5页South China Journal of Preventive Medicine

基　　金：希思科-臻和肿瘤精准治疗研究基金(Y-2019Genecast-067)

摘　　要：目的调查广州地区肺癌高危人群筛查依从性现状及影响因素,并分析肺癌筛查结果。方法选取2020年1月至2021年12月广州地区常住居民为研究对象,通过问卷收集其社会人口学资料及肺癌危险因素资料,筛查出肺癌高危人群,肺癌高危者由专业放射科医生进行低剂量螺旋CT(LDCT)扫描并根据诊断标准完成诊断。采用描述性分析方法对高危人群筛查依从性及筛查结果进行分析,并采用单、多因素分析方法对肺癌高危人群筛查依从性影响因素进行分析。结果17980名研究对象中肺癌高危评估率为19.96%(3589/17980),LDCT筛查依从率为34.99%(1256/3589)。3589例肺癌高危人员的肺癌确诊率为2.17%(78/3589),其中男性占61.54%(48/78),女性占38.46%(30/78),40~50岁占17.95%(14/78)、51~60岁占33.33%(26/78)、61~74岁占48.72%(38/78)。Logistic回归分析显示,女性(OR=2.130)、年龄越大(OR=1.408)、BMI≥24.0 kg/m2(OR=2.349、2.375)、中专及以上受教育程度(OR=2.008、3.251)、饮酒(OR=1.498)、吸烟(OR=2.239)、被动吸烟(OR=2.428)、有肺癌家族史(OR=2.081)、有慢性呼吸系统疾病史(OR=2.006)及不经常体育锻炼(OR=2.130)的肺癌高危者具有更高的筛查依从性。结论广州地区肺癌高危人群筛查依从性普遍较低,年龄、受教育程度、家族病史等均与筛查依从性有关,肺癌高危筛查有助于早期诊断肺癌及相关疾病,改善国民生活质量。Objective To investigate the status and influencing factors of screening compliance in high-risk populations of lung cancer in Guangzhou,and to analyze the results of lung cancer screening.Methods Permanent residents in Guangzhou from January 2020 to December 2021 were selected to conduct a questionnaire survey,collect their social demographic data and lung cancer risk factors,and screen out high-risk populations of lung cancer.The high-risk population of lung cancer was scanned with low-dose spiral CT(LDCT)by professional radiologists and diagnosed according to the diagnostic criteria.The descriptive analysis method was used to analyze the screening compliance and screening results of high-risk populations,and univariate and multivariate analysis methods were used to analyze the influencing factors of screening compliance of high-risk populations of lung cancer.Results Among 17980 residents,the high-risk rate of lung cancer was 19.96%(3589/17980),and the compliance rate of LDCT screening was 34.99%(1256/3589).The diagnostic rate of lung cancer in 3589 high-risk persons was 2.17%(78/3589),of which 61.54%(48/78)were male,38.46%(30/78)were female,17.95%(14/78)were 40 to 50 years old,33.33%(26/78)were 51 to 60 years old,and 48.72%(38/78)were 61 to 74 years old.Logistic regression analysis showed that the high-risk populations of lung cancer with female(OR=2.130),older(OR=1.408),body mass index≥24.0 kg/m2(OR=2.349,2.375),technical secondary school education or above(OR=2.008,3.251),alcohol consumption(OR=1.498),smoking(OR=2.239),passive smoking(OR=2.428),family history of lung cancer(OR=2.081),history of chronic respiratory diseases(OR=2.006),and infrequent exercise(OR=2.130)had higher screening compliance.Conclusions The screening compliance of high-risk populations of lung cancer in Guangzhou is generally low.Age,education level,and family history are all related to screening compliance.High-risk screening of lung cancer is helpful for early diagnosis of lung cancer and related diseases,and improves the quality o

关 键 词：肺癌高危筛查 依从性 影响因素 生活质量 

分 类 号：R195[医药卫生—卫生统计学]