基于临床和CT血管造影特征分析儿童多发性大动脉炎并发心功能不全危险因素  

Analysis of risk factors of Takayasu arteritis complicated with cardiac dysfunction in children based on clinical and CT angiography features

作　　者：马帅 王新宁[2] 闫淯淳 辛海燕[1] 孟念 刘海霞[1] 袁新宇[1] MA Shuai;WANG Xinning;YAN Yuchun;XIN Haiyan;MENG Nian;LIU Haixia;YUAN Xinyu(Department of Radiology,Children Hospital,Capital Institute of Pediatrics,Beijing 100020,China;Department of Rheumatology,Children Hospital,Capital Institute of Pediatrics,Beijing 100020,China)

机构地区：[1]首都儿科研究所附属儿童医院放射科,北京100020 [2]首都儿科研究所附属儿童医院风湿科,北京100020

出　　处：《中国介入影像与治疗学》2023年第3期171-174,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的基于临床和CT血管造影(CTA)特征分析儿童多发性大动脉炎(TA)并发心功能不全(CD)的危险因素。方法回顾性分析39例TA患儿,男9例、女30例,年龄1个月~15岁、中位年龄8岁。39例中,7例伴CD(CD组),均为女性,年龄2~15岁、中位年龄13岁;32例无CD(无CD组),男9例、女23例,年龄1个月~14岁、中位年龄7岁;对比分析2组患儿性别、年龄及主动脉受累部位等。结果2组患儿年龄分布范围差异有统计学意义(P<0.05)。高血压、升主动脉受累是TA患儿伴发CD的独立危险因素(P均<0.05),高血压及升主动脉受累TA患儿发生CD的概率分别为非高血压及无升主动脉受累者的14.493和13.889倍。结论高血压及升主动脉受累均为TA患儿伴发CD的独立危险因素,应积极予以干预。Objective To analyze the risk factors of Takayasu arteritis(TA)complicated with cardiac dysfunction(CD)in children based on clinical and CT angiography(CTA)features.Methods Data of 39 children with TA(including 9 boys and 30 girls)aged from 1 month to 15 years(with the median age of 8 years)were retrospectively analyzed.CD was found in 7 female cases(CD group)aged from 2 to 15 years with the median age of 13 years,but not in 32 cases with TA(non-CD group),including 9 males and 23 females aged from 1 month to 14 years(with the median age of 7 years).The gender,age and the location of arteries involvement were comparatively analyzed between groups.Results Significant different of age was found between groups(P<0.05).Hypertension and ascending aorta involvement were both independent risk factors of TA complicated with CD in children(both P<0.05).The probability of CD in TA children with hypertension and ascending aorta involvement was 14.493 times and 13.889 times of those without hypertension and ascending aorta involvement,respectively.Conclusion Both hypertension and ascending aorta involvement were independent risk factors of TA complicated with cardiac dysfunction in children,which should be actively intervened.

关 键 词：多发性大动脉炎 高血压 CT血管造影 心功能不全 

分 类 号：R725.4[医药卫生—儿科] R814.42[医药卫生—临床医学]