以发热为表现的14例亚急性甲状腺炎患者的临床特征分析  

Clinical characteristics of 14 patients with subacute thyroiditis characterized by fever

作　　者：许岩[1] 周永霞 徐玉峰[1] XU Yan;ZHOU Yongxia;XU Yufeng(Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210000;Nanjing Xuanwu District Xiaolingwei Community Health Service Center,Nanjing 210000,China)

机构地区：[1]南京中医药大学附属南京中医院,江苏南京210000 [2]南京市玄武区孝陵卫社区卫生服务中心,江苏南京210000

出　　处：《临床医学研究与实践》2023年第8期5-8,共4页Clinical Research and Practice

摘　　要：目的分析以发热为表现的14例亚急性甲状腺炎(SAT)患者的临床特征。方法选取2019年1月至2022年3月于南京中医药大学附属南京中医院感染性疾病科确诊为SAT的发热患者14例作为SAT组,另选取同期诊断为病毒性感染的发热患者28例作为病毒性感染组。分析并比较两组的临床特征及实验室检查指标。结果SAT患者多在夏、秋季发病;甲状腺超声检查6例为典型的片状不均匀低回声,7例为甲状腺弥漫性病变。SAT组的热程明显长于病毒性感染组,C-反应蛋白(CRP)水平、红细胞沉降率(ESR)明显高于病毒性感染组(P<0.05)。病毒性感染组的淋巴细胞比例明显高于SAT组(P<0.05)。SAT组的三碘甲状腺原氨酸(T3)、甲状腺素(T4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)水平明显高于病毒性感染组,促甲状腺激素(TSH)水平明显低于病毒性感染组(P<0.05)。结论临床遇到发热患者,伴或不伴咽痛、颈部疼痛,体温峰值、CRP水平、ESR较高,除感染性疾病外,须注意排查SAT。Objective To analyze the clinical characteristics of 14 patients with subacute thyroiditis(SAT)characterized by fever.Methods From January 2019 to March 2022,14 patients with fever diagnosed as SAT in the infectious diseases department of Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine were selected as SAT group,and 28 patients with fever diagnosed as viral infection at the same time were selected as viral infection group.The clinical characteristics and laboratory examination indexes of the two groups were analyzed and compared.Results SAT patients were more common in summer and autumn;thyroid ultrasonography showed 6 cases of typical patchy inhomogeneous low echo and 7 cases of diffuse thyroid lesions.The fever duration in the SAT group was significantly longer than that in the viral infection group,and the level of C-reactive protein(CRP),erythrocyte sedimentation rate(ESR)were significantly higher than those in the viral infection group(P<0.05).The proportion of lymphocytes in the viral infection group was significantly higher than that in the SAT group(P<0.05).The levels of triiodothyronine(T3),thyroxine(T4),free triiodothyronine(FT3)and free thyroxine(FT4)in the SAT group were significantly higher than those in the viral infection group,and the level of thyroid stimulating hormone(TSH)was significantly lower than that in the viral infection group(P<0.05).Conclusion In clinical practice,patients with fever,with or without sore throat and neck pain,high peak body temperature,CRP level and ESR,except for infectious diseases,should pay attention to screening SAT.

关 键 词：发热 亚急性甲状腺炎 病毒性感染 C-反应蛋白 红细胞沉降率 

分 类 号：R581.4[医药卫生—内分泌]