早期营养管理对急性胰腺炎患者预后及TBIL、CRP、RDW的影响  

Effect of early nutrition management on prognosis and TBIL,CRP,RDW in patients with acute pancreatitis

作　　者：李野[1] 勾洋[1] 郝妍[1] LI Ye;GOU Yang;HAO Yan(The Emergency Department,Beijing jishuitan hospital,Beijing,China,100096)

机构地区：[1]北京积水潭医院急诊科,北京100096

出　　处：《分子诊断与治疗杂志》2023年第2期294-297,共4页Journal of Molecular Diagnostics and Therapy

基　　金：院级科研项目研究课题(HL202206)。

摘　　要：目的 探究早期营养管理对急性胰腺炎患者预后及总胆红素(TBIL)、C反应蛋白(CRP)、红细胞分布宽度(RDW)的影响。方法 选取2021年8月至2022年3月北京积水潭医院的急性胰腺炎患者129例为研究对象,采用随机数字表法分为对照组(n=64)与观察组(n=65),对照组患者给予常规护理,观察组患者在常规护理的基础上予以早期营养管理,两组均护理至出院日。记录两组肠功能恢复时间,比较两组干预前后Ranson评分、TBIL、CRP、RDW及预后情况。结果 观察组肠鸣音消失时间、排气和腹胀恢复所需时间均短于对照组,差异均具有统计学意义(t=10.866、2.834、5.759,P<0.05)。干预前,两组Ranson评分、TBIL、CRP、RDW水平比较,差异无统计学意义(t=0.974、0.305、0.808、0.212,P>0.05);干预后,两组Ranson评分、TBIL、CRP、RDW水平均降低,且观察组低于对照组,差异均具有统计学意义(t=3.819、2.069、9.170、2.094,P<0.05)。观察组并发症发生率6.15%(4/65)显著高于对照组18.75%(12/64),差异有统计学意义(χ^(2)=4.709,P<0.05)。结论 早期营养管理可缩短急性胰腺炎患者肠功能恢复时间,改善TBIL、CRP、RDW水平及预后。Objective To investigate the effect of early nutrition management on the prognosis,total bilirubin(TBIL),C-reactive protein(CRP)and red blood cell distribution width(RDW)of patients with acute pancreatitis. Methods A total of 129 patients with acute pancreatitis in Beijing Jishuitan Hospital from August 2021 to March 2022 were selected as the research objects. They were randomly divided into the control group(n=64)and the observation group(n=65)by using the random number table. The patients in the control group were given routine care,and the patients in the observation group were given early nutrition management based on routine care. Both groups were nursed until the day of discharge. The recovery time of intestinal function was recorded,and the Ranson score,TBIL,CRP,RDW and prognosis were compared between the two groups before and after intervention. Results The disappearance time of bowel sounds and the recovery time of exhaust and abdominal distension in the observation group were shorter than those in the control group,and the differences were statistically significant(t=10.866、2.834、5.759,P<0.05). Before the intervention,there was no significant difference in the levels of Ranson score,TBIL,CRP and RDW between the two groups(t=0.974、0.305、0.808、0.212,P>0.05). After the intervention,the levels of Ranson score,TBIL,CRP,and RDW in both groups decreased,and the observation group was lower than the control group,with statistically significant differences(t=3.819、2.069、9.170、2.094,P<0.05). The incidence of complications in the observation group was 6.15%(4/65),which was significantly higher than that in the control group18.75%(12/64),with a statistically significant difference(χ^(2)=4.709,P<0.05). Conclusion Early nutrition management can shorten the recovery time of intestinal function,improve the levels of TBIL,CRP,RDW and prognosis in patients with acute pancreatitis.

关 键 词：营养管理 急性胰腺炎 C反应蛋白 红细胞分布宽度 总胆红素 

分 类 号：R473.5[医药卫生—护理学]