露水草植物蜕皮甾酮类化学成分及其药理作用研究进展  

Research progress in chemical constituents and pharmacological effects of phytoecdysterone from Cyanotis arachnoidea

作　　者：胡婧楠 冯玉 田义龙[2,3,4] 王鑫国 牛丽颖[2,3,4] HU Jingnan;FENG Yu;TIAN Yilong;WANG Xinguo;NIU Liying(Affiliated Hospital of Hebei University of Chinese Medicine,Shijiazhuang Hebei 050011,China;Hebei University of Chinese Medicine,Shijiazhuang Hebei 050091,China;Hebei TCM Formula Granule Innovation Center,Shijiazhuang Hebei 050091,China;Hebei TCM Quality Evaluation,Standardization Engineering Research Center,Shijiazhuang Hebei 050091,China)

机构地区：[1]河北中医学院附属医院,河北石家庄050011 [2]河北中医学院,河北石家庄050091 [3]河北省中药配方颗粒技术创新中心,河北石家庄050091 [4]河北省中药材品质评价与标准化工程研究中心,河北石家庄050091

出　　处：《中国药物警戒》2023年第2期231-235,共5页Chinese Journal of Pharmacovigilance

基　　金：中央引导地方科技发展资金项目(206Z2501G);河北省自然科学基金资助项目(H2019423050);河北省中医药管理局科研计划项目(2020017)。

摘　　要：露水草是鸭跖草科蓝耳草属一种多年生草本植物,属于彝族药的一种,植物蜕皮甾酮是露水草的主要活性成分之一,目前已鉴定出植物蜕皮甾酮、植物甾醇、植物甾酮苷、脂肪酸、萜及挥发油等多种化学成分,其中植物蜕皮甾酮的含量最为显著。植物蜕皮甾酮具有广泛的生物活性,在抗炎、抗肿瘤、保护神经系统、降低血糖血脂、心血管、骨骼系统以及器官保护等方面作用显著。本文总结了露水草中植物蜕皮甾酮类化学成分及其生物活性,为露水草的深度开发利用提供参考。Cyanotis arachnoidea,a type of Yi medicine,is a perennial herb belonging to the Cyanotis D.Don of Commelinaceae.Phytoecdysterone is one of the main active components of Cyanotis arachnoidea.So far,phytoecdysteroids,phytosterol,phytosterone glycoside,fatty acid,terpene and volatile oil have been identified as the main chemical constituents of Cyanotis arachnoidea.Among these chemical constituents,phytoecdysterone has the most significant content.Phytoecdysterone has a wide range of biological activities,such as anti-inflammatory and anti-tumor properties,protection of the nervous system,reduction of blood glucose and lipid,and protection of cardiovascular and skeletal systems and organs.In this paper,the phytoecdysterone constituents of Cyanotis arachnoidea and the biological activities of phytoecdysterone were summarized in order to provide reference for the development and utilization of Cyanotis arachnoidea.

关 键 词：彝族药 露水草 植物蜕皮甾酮 化学成分 药理作用 

分 类 号：R961[医药卫生—药理学] R994.1[医药卫生—药学]