桃仁红花煎治疗心血瘀阻证冠心病稳定性心绞痛临床研究  

Clinical Study on Taoren Honghua Decoction for Stable Angina Pectoris of Coronary Heart Disease with Heart Blood Stasis Obstruction Syndrome

作　　者：夏婵娟 杨君 华依梦 XIA Chanjuan;YANG Jun;HUA Yimeng

机构地区：[1]浙江省荣军医院中药房,浙江嘉兴314000 [2]浙江省荣军医院中医科,浙江嘉兴314000

出　　处：《新中医》2023年第4期30-33,共4页New Chinese Medicine

摘　　要：目的:观察桃仁红花煎治疗心血瘀阻证冠心病稳定性心绞痛的临床疗效。方法:选择心血瘀阻证冠心病稳定性心绞痛患者82例为研究对象,按随机数字表法分为治疗组和对照组各41例。对照组予阿司匹林、他汀类降脂药、血管紧张素Ⅱ受体拮抗剂、血管紧张素转化酶抑制剂等西医常规治疗,治疗组在对照组的基础上给予桃仁红花煎内服。2组疗程均为8周。比较2组心功能指标[左室射血分数(LVEF)、左室收缩末期内径(LVESD)、心排血量(CO)]水平、心血瘀阻证证候评分及总体临床疗效。结果:治疗组总有效率为95.12%,明显高于对照组75.61%,组间比较,差异有统计学意义(P<0.05)。治疗后,2组LVEF、CO水平均较治疗前明显升高(P<0.05),LVESD水平较治疗前明显降低(P<0.05),且治疗组以上心功能指标改善均明显优于对照组(P<0.05)。治疗前,2组胸刺痛、胸闷、心悸、唇舌紫暗评分比较,差异无统计学意义(P>0.05);治疗后,2组上述各项中医证候评分均较治疗前明显降低(P<0.05),且治疗组各项评分均明显低于对照组(P<0.05)。结论:在西医常规治疗基础上给予桃仁红花煎可进一步改善心血瘀阻证冠心病稳定性心绞痛患者的心功能和中医证候,提高临床疗效。Objective:To observe the clinical effect of Taoren Honghua Decoction for stable angina pectoris of coronary heart disease with heart blood stasis obstruction syndrome.Methods:A total of82 cases of patients with stable angina pectoris of coronary heart disease with heart blood stasis obstruction syndrome were selected as the study subjects and divided into the treatment group and the control group according to the random number table method,with 41 cases in each group.The control group was given routine treatment in western medicine including Aspirin,Atorvastatin,angiotensin Ⅱ receptor antagonist and angiotensin converting enzyme inhibitor,and the treatment group was additionally given oral administration of Taoren Honghua Decoction based on the treatment of the control group.Both groups were treated for 8 weeks.The indexes of heart function including left ventricular ejection fraction(LVEF),left ventricular end-systolic dimension(LVESD)and cardiac output(CO),the syndrome scores of heart blood stasis obstruction syndrome and the total clinical effect were compared between the two groups.Results:The total effective rate was 95.12% in the treatment group,significantly higher than that of 75.61% in the control group,the difference being significant(P<0.05).After treatment,LVEF and CO in the two groups were significantly increased when compared with those before treatment(P<0.05),and LVESD was significantly decreased when compared with those before treatment(P<0.05);the improvement of the above indexes of heart function in the treatment group was significantly better than that in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of scores of stabbing pain in the chest,chest discomfort,palpitations,and purple,dusky tongue and lips between the two groups(P>0.05).After treatment,the above syndrome scores in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the scores in the treatment group were significantly lower

关 键 词：冠心病 心绞痛 心血瘀阻证 桃仁红花煎 心功能 

分 类 号：R541.4[医药卫生—心血管疾病]