心脉隆注射液在慢性肺源性心脏病患者中的应用效果  

Application Effect of Xinmailong Injection in Patients with Chronic Pulmonary Heart Disease

作　　者：岳刚 Yue Gang(Department of Respiratory Medicine,Xuzhou City Tongshan District Hospital of Traditional Chinese Medicine,Xuzhou 221116,Jiangsu Province,China)

机构地区：[1]徐州市铜山区中医院呼吸科,江苏徐州221116

出　　处：《中国社区医师》2023年第4期64-66,共3页Chinese Community Doctors

摘　　要：目的:探析心脉隆注射液在慢性肺源性心脏病患者中的应用效果。方法:选取2019年6月-2022年2月在徐州市铜山区中医院住院治疗的52例慢性肺源性心脏病患者为研究对象,根据入院先后顺序分为对照组与观察组,各26例。对照组予以常规治疗,观察组在对照组基础上予以心脉隆注射液治疗,比较两组前列环素、血栓素A2、血清白细胞介素6(IL-6)、干扰素γ(IFN-γ)、动脉血氧分压(PaO_(2))和动脉二氧化碳分压(PaCO_(2))水平。结果:治疗前,两组前列环素和血栓素A2水平比较,差异无统计学意义(P>0.05);治疗后,观察组前列环素水平高于对照组,血栓素A2水平低于对照组,差异有统计学意义(P<0.001)。治疗前,两组IL-6、IFN-γ水平比较,差异无统计学意义(P>0.05);治疗后,观察组IL-6水平低于对照组,IFN-γ水平高于对照组,差异有统计学意义(P<0.001)。治疗前,两组PaO_(2)和PaCO_(2)水平比较,差异无统计学意义(P>0.05);治疗后,观察组PaO_(2)水平高于对照组,PaCO_(2)水平低于对照组,差异有统计学意义(P<0.001)。结论:对慢性肺源性心脏病患者采用心脉隆注射液治疗,可改善患者心功能和血管内皮功能,提高患者预后效果。Objective:To explore the application effect of Xinmailong injection in patients with chronic pulmonary heart disease.Methods:A total of 52 patients with chronic pulmonary heart disease who were hospitalized in Xuzhou City Tongshan District Hospital of Traditional Chinese Medicine from June 2019 to February 2022 were selected as the study subjects.They were divided into control group and observation group according to the order of admission,with 26 cases in each group.The control group was given conventional therapy,and the observation group was treated with Xinmailong injection on the basis of control group.The levels of prostacyclin,thromboxane A2,serum interleukin-6(IL-6),and interferon-γ(IFN-γ),arterial partial pressure of oxygen(PaO_(2))and arterial partial pressure of carbon dioxide(PaCO_(2))were compared between two groups.Results:There was no significant difference in the levels of prostacyclin and thromboxane A2 between the two groups before treatment(P>0.05);After treatment,the level of prostacyclin in the observation group was higher than that in the control group,and the level of thromboxane A2 in the observation group was lower than that in the control group,with statistically significant difference(P<0.001).There was no significant difference in the levels of IL-6 and IFN between two groups before treatment(P>0.05);After treatment,the IL-6 level in the observation group was lower than that in the control group,and the level of IFN-γin the observation group was higher than that in the control group,and the difference was statistically significant(P<0.001).There was no significant difference in PaO_(2) and PaCO_(2) levels between the two groups before treatment;After treatment,the PaO_(2) level in the observation group was higher than that in the control group,and the PaCO_(2) level in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.001).Conclusion:Xinmailong injection in the treatment of patients with chronic pulmonary heart diseas

关 键 词：慢性肺源性心脏病 心脉隆注射液 前列环素 血栓素 

分 类 号：R541.5[医药卫生—心血管疾病]