四川省五地市45岁及以上男性人群HIV感染情况及相关因素分析  

Analysis of HIV infection and related factors among men aged 45 and above in five cities of Sichuan province

作　　者：王俊杰[1] 田春华 黄玉玲 曾亚莉[2] 赖文红[2] WANG Jun-jie;TIAN Chun-hua;HUANG Yu-ling;ZENG Ya-li;LAI Wen-hong(National Center for AIDS/STD Control and Prevention,China CDC,Beijing 102206,China;不详)

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [2]四川省疾病预防控制中心性病艾滋病防治所,四川成都610041 [3]四川省性病艾滋病防治协会秘书处,四川成都610041

出　　处：《中国病毒病杂志》2022年第6期437-443,共7页Chinese Journal of Viral Diseases

基　　金：国家卫生健康委疾病预防控制局老年艾滋病防治策略研究项目(2021-5-流病室-007);四川性社会学与性教育研究中心2020年重点项目(SXJYA2001)。

摘　　要：目的 深入了解四川省5个地市中老年男性艾滋病防控意识、高危性行为以及艾滋病感染情况,分析艾滋病感染的相关因素,为相关策略措施的制定提供参考。方法 选择在四川省广元市、遂宁市、宜宾市、自贡市、绵阳市城区商业街头、公园广场、娱乐场所、发廊、按摩店、旅社、出租屋等场所活动且年龄≥45岁的男性作为研究对象,通过社会组织或社区小组,运用场所招募、同伴推动、方便抽样等方式,调查收集社会人口学特征、性态度、高危性行为、艾滋病检测等情况,采集血液样本进行人类免疫缺陷病毒(human immunodeficiency virus,HIV)检测。运用SPSS 19.0软件进行统计分析,采用单因素和多因素非条件logistic回归分析HIV感染相关因素。结果 共调查检测5个地市1 884名男性,HIV抗体阳性率为0.9%(17/1 884),45.3%(853/1 884)近1年内有商业性行为史,47.1%(887/1 884)近1年未接受过HIV抗体检测。HIV感染的多因素分析结果显示,近1年商业性行为中从未使用安全套者HIV感染风险是每次均使用者的16.289倍(OR=16.289,95%CI:3.318~79.970,P=0.001),近1年有临时性伴的性行为者HIV感染风险是没有临时性伴性行为者的3.200倍(OR=3.200, 95%CI:1.103~9.284,P=0.032)。结论 调查地区在商业街头、场所活动的45岁以上中老年男性存在不安全性行为,未进行HIV检测的比例较高,艾滋病传播风险较大,需要加强警惕性教育,提高防范意识,丰富业余生活,加强关怀和沟通,提高家庭和性责任意识,保持性伴忠贞,倡导安全的性行为,动员有高危性行为的人群及时进行艾滋病检测。Objective To understand the status of HIV infection,high-risk sexual behaviors and the relevant factors of HIV infection among middle-aged and older males in five cities of Sichuan province.Methods Men aged≥45 years old who frequently made appearance in city commercial area,parks,entertainment places,salons and spas,hotels,rental houses in Guangyuan,Suining,Yibin,Zigong and Mianyang of Sichuan province were recruited in the study by social organizations or community groups through site recruitment method,respondent-driven sampling method and convenient sampling method.A questionnaire survey was conducted to collect social demographic information,sexual attitudes,high-risk sexual behaviors and HIV testing.Blood samples were also collected for HIV testing.SPSS 19.0 software was used for data statistical analysis,univariate and multivariate non conditional logistic regression models were used to analyze the relevant factors for HIV infection.Results A total of 1884 men were recruited with the overall HIV antibody positive rate of 0.9%(17/1 884).45.3%(853/1 884) subjects had commercial sex and 47.1%(887/1 884) had not been tested for HIV antibodies in the past 1 year.Multivariate logistic regression analysis showed that the risk of HIV infection among men who had sex without using condoms was 16.289 times of those with condom use during each sex intercourse(OR=16.289,95% CI:3.318—79.970,P=0.001) in the past 1 year,and the risk of HIV infection among men who had temporary sexual partners was 3.200 times of those who did not have(OR=3.200,95 %CI:1.103—9.284,P=0.032).Conclusions Men aged 45and over who have unsafe commercial sex are at high risk of HIV infection.Therefore,it is necessary to strengthen health education and behavioral intervention,prevent extramarital sexual behaviors,encourage condom use and regular HIV testing in order to reduce the risk of HIV infection.

关 键 词：艾滋病 HIV 中老年 男性 相关因素 

分 类 号：R512.91[医药卫生—内科学]