存活小下颌畸形患儿产前影像学诊断意义  

The Diagnostic Significance of Prenatal Imaging Examination in Survived Mandibular Micrognathia Children

作　　者：魏立爽 周一敏[1] 徐琼[2] 任聪聪 Wei Lishuang;Zhou Yimin;Xu Qiong;Ren Congcong(Department of Ultrasound,Women's Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China;Department of Radiology,Women's Hospital,School of Medicine,Zhejiang University,Hangzhou 310006,China)

机构地区：[1]浙江大学医学院附属妇产科医院超声科,杭州市310006 [2]浙江大学医学院附属妇产科医院放射科,杭州市310006

出　　处：《中国超声医学杂志》2023年第2期230-233,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 探讨超声(US)及磁共振(MRI)影像学筛查对存活小下颌畸形(MM)患儿及合并异常的产前诊断意义。方法 回顾性分析行产前检查诊断为MM并活产患儿的产前影像学资料、临床资料及产后随访资料,总结产前US及MRI对MM及合并异常的检出准确度。结果 共检索出产前影像学考虑为MM且存活患儿6例。病例1有家族史,产前US诊断MM,MRI补充诊断腭裂、舌后坠,产后考虑单纯性皮罗序列征(PRS),MRI与产后一致;病例2无家族史,产前US诊断MM,合并循环系统非致死性异常,MRI仅诊断MM,US与产后一致;病例3无家族史,产前US仅诊断MM,未行MRI,产后补充问号耳,考虑耳髁突综合征(另一病例MRI补充耳后皮赘,即问号耳);病例4、5无家族史,产前US诊断MM,未行MRI,US与产后一致;病例6无家族史,产前US诊断MM,未行MRI,产后补充腭裂。结论 产前US可筛查存活MM患儿合并的其他系统异常,产前US可筛查MRI未发现的循环系统异常。产前MRI可筛查存活MM患儿合并腭裂、舌后坠及问号耳的颜面异常。产前影像学诊断可为MM妊娠结局的选择提供参考。Objective This study investigated the diagnostic significance of Ultrasound(US) and Magnetic Resonance Imaging(MRI) screening for MM and its supplementary malformation in survived mandibular micrognathia(MM) children. Methods We reviewed the prenatal imaging, clinical data, and postpartum follow-up data of fetuses who were diagnosed with MM during prenatal examination, to summarize the accuracy of prenatal US and MRI for MM and associated abnormalities in survived MM children. Results We found 6 survived fetuses who were considered to be MM in the prenatal imaging diagnosis in our hospital. Case 1 had a family medical history, who was diagnosed as MM by prenatal US. Supplementary cleft palate and glossoptosis was diagnosed with MRI, which were consistent with the postpartum diagnosis of Pierre Robin sequence(PRS);Case 2 had no family medical history. MM and non-fatal abnormality of circulatory system was diagnosed as by prenatal US. MRI only identified MM. US screening was consistent with postpartum diagnosis;Case 3 had no family history. Prenatal US only diagnosed MM. No MRI screening was performed. Postpartum diagnosis supplemented “question mark ear”(QME), which was considered as Auriculocondylar syndrome(such another case of this syndrome was supplementarily diagnosed by MRI with post-ear skin tag, namely QME);Case 4 and 5 had no family medical history, who were diagnosed as MM with US. This was consistent with postpartum diagnosis. No MRI screening was performed. Case 6 had no family medical history. US found MM, No MRI was performed. Cleft palate was found in postpartum supplementary diagnosis. Conclusions Prenatal US can identify the supplementary abnormalities of other systems in the fetus period of survived MM children. It is also useful to detect the circulatory system’s abnormalities that might not be detected by MRI. Prenatal MRI is useful for detecting facial abnormalities such as cleft palate, glossoptosis and QME, in survived MM children. Prenatal imaging diagnosis can be used as a reference

关 键 词：小下颌畸形 存活 产前US诊断 产前MRI诊断 

分 类 号：R714.53[医药卫生—妇产科学] R445.1[医药卫生—临床医学]