输尿管软镜下腔内碎石术对上尿路结石的碎石效果及尿源性脓毒血症发生的影响  

Effect of Ureteroscopic Intraluminal Lithotripsy on Upper Urinary Tract Stones and Urinary Sepsis

作　　者：冯伟[1] 吕忠[1] FENG Wei;LYU Zhong(Department of Urology,Changzhou Wujin People's Hospital,Changzhou Jiangsu 213000)

机构地区：[1]常州市武进人民医院泌尿外科,江苏常州213000

出　　处：《医学临床研究》2023年第2期202-204,208,共4页Journal of Clinical Research

摘　　要：【目的】探讨输尿管软镜下腔内碎石术用于上尿路结石的疗效及对尿源性脓毒血症发生的影响。【方法】入住本院的120例上尿路结石患者,随机分为对照组和观察组,每组60例。对照组采用经皮肾镜取石术,观察组采用输尿管软镜下腔内碎石术,比较两组患者手术情况、临床疗效、感染相关指标及尿源性脓毒血症发生率。【结果】观察组手术时间短于对照组,术中出血量少于对照组,术后住院时间短于对照组,且差异均有统计学意义(P<0.05);观察组尿源性脓毒血症发生率低于照组,碎石成功率、结石清除率高于对照组,且差异有统计学意义(P<0.05);观察组患者术后2 h白细胞计数(WBC)、中性粒细胞计数(N)、血清降钙素原(PCT)均低于对照组(P<0.05)。【结论】输尿管软镜下腔内碎石术用于上尿路结石术患者,具有更优的碎石成功率、结石清除率,患者术后感染风险低,且对尿源性脓毒血症发生具有一定的预防价值。【Objective】To analyze the effect of ureteroscopic intraluminal lithotripsy on upper urinary calculi and prevention of sepsis.【Methods】A total of 120 patients with upper urinary calculi were divided into the control group and the observation group,with 60 cases in each group.Patients in the control group received percutaneous nephrolithotripsy,while patients in thr observation group were treated with ureteroscopic intraluminal lithotripsy.Surgical conditions,clinical efficacy,infection-related indicators and incidence of urogenic sepsis were compared between the two groups.【Results】The operation time in the observation group was shorter than that in the control group.The intraoperative blood loss in the observation group was less than that in the control group;And postoperative hospital time was shorter than that in the control group as well.The differences were statistically significant(P<0.05).The gravel success rate and stone clearance rate in the observation group were higher than those in the control group.Postoperative 2 h leukocyte count(WBC),neutrophil count(N)and serum Calcitonogen(PCT)in the observation group were lower than those in the control group(P<0.05).【Conclusion】Uteroscopic endoscopic lithotripsy is used in patients with upper urinary calculi,which provides higher s gravel success rate and better stone removal rate,and reduce the risk of postoperative infection.It has certain clinical value for the prevention of urogenic sepsis.

关 键 词：尿路结石症/外科学 输尿管镜检查 尿路结石症/并发症 脓毒症/并发症 治疗结果 

分 类 号：R691.4[医药卫生—泌尿科学]