2种不同乳脂球膜对小鼠智力、抗疲劳及抗氧化功能的作用  

Nootropic,Antifatigue and Antioxidant Effects of Two Commercial Milk Fat Globule Membranes in Mice

作　　者：温欣怡 邹潇潇 罗永康[1] 谭雨青 WEN Xinyi;ZOU Xiaoxiao;LUO Yongkang;TAN Yuqing(College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083,China)

机构地区：[1]中国农业大学食品科学与营养工程学院,北京100083

出　　处：《乳业科学与技术》2023年第1期1-8,共8页JOURNAL OF DAIRY SCIENCE AND TECHNOLOGY

基　　金：“十三五”国家重点研发计划重点专项(2017YFD0400201)。

摘　　要：以2种不同的乳脂球膜为原料,以BALB/c雄性小鼠作为动物模型,分别设定2个不同的乳脂球膜处理组和空白组进行对照,探究不同乳脂球膜对小鼠益智、抗疲劳和抗氧化的改善作用及可能的机制。结果表明:乳脂球膜能够提高小鼠学习认知能力和空间记忆能力,延长小鼠的力竭游泳时间,显著提高糖原含量和改善与疲劳和氧化应激有关的各项指标,表明乳脂球膜有益智功能,可以提高机体的抗氧化能力,具有抗疲劳和抗氧化的营养功能,不同加工处理和含有不同成分的乳脂球膜产品的改善效果存在差异。In this study,the nootropic,antifatigue and antioxidant effects of two commercial milk fat globule membranes(MFGM)in BALB/c male mice were evaluated and the possible mechanisms were elucidated.Normal saline was used a control.The experimental results showed that MFGM could improve learning and cognitive ability spatial memory ability in mice,extend exhaustive swimming time,significantly increase glycogen levels,and greatly improve fatigue-and oxidative stress-related indicators,indicating its nootropic,antifatigue and antioxidant effects.However,the effects of the two MFGMs,which are produced by different methods and have different compositions,were different.

关 键 词：乳脂球膜 益智 抗疲劳 抗氧化 

分 类 号：TS252.1[轻工技术与工程—农产品加工及贮藏工程]