质谱技术在微塑料分析领域的发展及应用  

Development and Application of Mass Spectrometry in Microplastics Analysis

作　　者：贾菲菲 赵耀[2] 汪福意[2,3,4] JIA Fei-fei;ZHAO Yao;WANG Fu-yi(National Institute for Food and Drug Control,Beijing 100050,China;Beijing National Laboratory for Molecular Sciences,CAS Key Laboratory of Analytical Chemistry for Living Biosystems,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,China;University of Chinese Academy of Sciences,Beijing 100049,China;National Centre for Mass Spectrometry in Beijing,Beijing 100190,China)

机构地区：[1]中国食品药品检定研究院,北京100050 [2]中国科学院化学研究所活体分析化学实验室,北京分子科学国家研究中心,北京100190 [3]中国科学院大学,北京100049 [4]北京质谱中心,北京100190

出　　处：《质谱学报》2023年第2期131-145,共15页Journal of Chinese Mass Spectrometry Society

基　　金：国家自然科学基金(21927804)。

摘　　要：微塑料一般指微纳米尺度的高分子聚合物,由于其普遍存在于环境中,易被生物摄入,且可能存在化学毒性,使得微塑料污染成为重要的全球环境问题。近年来,微纳米尺度塑料表征分析方法发展迅速,如粒度测定、化学鉴定和定量分析等,质谱技术已越来越多地用于微塑料的检测。本文主要介绍质谱技术在微塑料分析中的最新应用进展,阐述各类质谱及前处理技术用于微塑料定性、定量分析的原理和特点。随着质谱技术的不断发展,与其他表征手段联用方法的不断开发和应用,质谱技术将在微塑料检测领域发挥越来越重要的作用。Microplastics are high molecular-weight polymers with micro-or nano-meter size,which have become a major global environmental issue in recent decades due to their ubiquity in the environment,bioavailability and potential toxicity.New analytical methods for the characterization of microplastics and nanoplastics are quickly emerging,such as particle size measurement,component identification and quantification.Many techniques have been developed and applied for the characterization of microplastics,such as Fourier-transform infrared spectroscopy,Raman spectroscopy and mass spectrometry(MS),etc.In recent years,the continuous development of MS technology has drawn more and more attention to the characterization and the environmental impact of microplastics.This paper mainly reviewed the state-of-the-art development and application of MS in microplastics analysis during the past decade.The principles and characteristics of various MS techniques used in the qualitative and quantitative analysis of microplastics were described,including thermal analysis coupled with MS-based techniques,elemental analytical MS,MALDI-ToF MS,LC-MS and ToF-SIMS.MS can provide chemical structure,molecular weight,degree of polymerization,additives,main functional groups and other information about the polymers,so it can be widely applied for chemical characterization,particle size determination and semi-quantitative/quantitative analysis of microplastics of small size.It has the advantages of replicable,fast real-time in situ analysis and high throughput detection,which can not only detect microplastics in the environment but also in biological tissues or cells in situ,showing great application potential in the research on the source,migration,transformation and interaction with biological organisms.The microplastics have been detected in the ocean,atmosphere,soil,consumer products,organisms and even human tissue,including polyethylene,polyamide,polyvinyl chloride,polypropylene,polystyrene,polycarbonate,polymethyl methacrylate,polyethylene ter

关 键 词：微塑料 质谱(MS) 检测技术 样品制备 

分 类 号：O657.63[理学—分析化学]