三氧自体输血对改善脑卒中恢复期患者运动功能的疗效分析  

Efficacy of autologous ozoneized blood transfusion in improving motor function in convalescent stroke patients

作　　者：陈扬 吴群强 李颖 王晓清 穆士杰 赵树铭 CHEN Yang;WU Qunqiang;LI Ying;WANG Xiaoqing;MU Shijie;ZHAO Shuming(Department of Blood Transfusion,Second Affiliated Hospital of Air Force Military Medical University,Xi'an 710038,China;Department of Rehabilitation,Second Affiliated Hospital of Air Force Military Medical University,Xi'an 710038,China;Guiqian International General Hospital)

机构地区：[1]空军军医大学第二附属医院输血科,陕西西安710038 [2]空军军医大学第二附属医院康复科,陕西西安710038 [3]贵黔国际总医院

出　　处：《中国输血杂志》2023年第2期105-108,共4页Chinese Journal of Blood Transfusion

摘　　要：目的探讨三氧自体输血在改善脑卒中恢复期患者意识状态和运动功能中的疗效。方法选取2016年8月~2021年9月在本院康复科接受治疗并确诊为脑卒中恢复期的患者共44例,采用盲法随机分为实验组(n=22,三氧自体输血治疗,采集患者肘正中静脉血200 mL,间隔2~3 d 1次,12次为1个疗程,同时进行一般康复训练(即运动疗法、作业疗法、针灸治疗、经颅磁刺激技术治疗)和对照组(一般康复训练),对2组患者治疗前后的意识状态(GCS评分)、日常生活能力(Barthel指数评分)得分情况统计与比较分析,并观察评估上田敏运动功能分级、Brunnstrom分期、肌张力分级。结果实验(治疗)结束后,实验组与对照组比较:1)GCS评分为14.82±0.39 vs 12.41±2.52、Barthel评分为61.14±12.24 vs 52.05±11.72(P<0.05);2)运动功能恢复率为95.45%(21/22)vs 63.64%(14/22)(P<0.05);3)肌张力总恢复率为90.91%(20/22)vs 63.64%(14/22)(P<0.05)。结论三氧自体输血对于脑卒中恢复期患者的意识状态、运动功能和肌张力有一定的改善作用,具备较高的安全性和有效性。Objective To investigate the efficacy of autologous ozoneized blood transfusion(AOBT)in improving consciousness and motor function in convalescent stroke patients.Methods A total of 44 patients who were diagnosed as convalescent cerebral apoplexy and received treatment in Rehabilitation Department of our hospital from August 2016 to September 2021 were randomly divided into the experimental group and control group by blind method.The experimental group(n=22)received general rehabilitation training(such as exercises,occupational therapy,acupuncture and transcranial magnetic stimulation)plus AOBT(200 mL venous phlebotomy at the median elbow),once every 2 to 3 days and 12 occasions as a course of treatment;the control group solely recieved general rehabilitation training.The consciousness(GCS score)and ability of daily living(Barthel index score)score of the two groups before and after treatment were statistically compared,and Ueda motor function grade,Brunnstrom stage and muscle tone grade were observed and evaluated.Results After the treatment,the experimental group and the control were compared as follows:1)the GCS score and Barthel score was 14.82±0.39 vs 12.41±2.52,61.14±12.24 vs 52.05±11.72(P<0.05);2)The recovery rate of motor function was 95.45%(21/22)vs 63.64%(14/22)(P<0.05);3)The total recovery rate of muscle tone was 90.91%(20/22)vs 63.64%(14/22)(P<0.05).Conclusion AOBT,with somewhat high safety and effectiveness,can improve the state of consciousness,motor function and muscle tone in convalescent patients with stroke.

关 键 词：三氧治疗 脑卒中恢复 自体输血 意识状态 运动功能 

分 类 号：R457.1[医药卫生—治疗学] R459.6[医药卫生—临床医学] R743.3