宫颈小细胞神经内分泌癌的临床及影像表现分析  

Clinical and imaging features of small cell neuroendocrine carcinoma of the uterine cervix

作　　者：蒋赵娟 贺银付 李振辉[1] 李清婉 高德培[1] JIANG Zhao-juan;HE Yin-fu;LI Zhen-hui(Department of Radiology,the Third Affiliated Hospital of Kunming Medical University,Yunnan Cancer Hospital,Kunming 650118,China)

机构地区：[1]昆明医科大学第三附属医院(云南省肿瘤医院),昆明650118

出　　处：《放射学实践》2023年第3期313-317,共5页Radiologic Practice

基　　金：甘肃省卫生健康行业科研计划项目(GSWSKY2021-059)。

摘　　要：目的:总结宫颈小细胞神经内分泌癌的临床及影像表现。方法:回顾性分析经病理学确诊为宫颈小细胞神经内分泌癌的33例患者的临床资料与MRI及CT图像特征。结果:33例宫颈小细胞神经内分泌癌患者中淋巴结转移者占42.4%,HPV阳性者占82.4%。33例患者中81.8%为外生性,18.2%为内生性,外生性肿块中5例呈类圆形及类椭圆形,22例呈不规则形及分叶形。肿块的CT表现呈不均匀的轻度到中度强化,MRI表现呈等T 1稍长T 2信号且T 2信号均匀,病灶DWI呈高信号,ADC值平均值为(0.54±0.11)×10^(-3)mm^(2)/s。结论:宫颈小细胞神经内分泌癌影像表现多为外生性肿块,CT及MRI增强呈不均匀强化,其中CT多呈轻中度强化,MRI呈等T 1稍长T 2信号,信号较为均匀,DWI明显扩散受限。Objective:To summarize the clinical and imaging features of small cell neuroendocrine carcinoma of the uterine cervix(SCNECC).Methods:The clinical manifestations,CT and MRI findings of 33 patients with pathologically confirmed SCNECC were retrospectively reviewed.Results:Among 33 patients with SCNECC,42.4%had lymph node metastasis,82.4%were HPV positive,81.8%were endogenous,and 18.2%were exogenous.Among 27 patients with endogenous SCNECC,the lesions were round or oval in 5 and lobulated or irregular in 22.The tumors showed heterogeneous mild to moderate enhancement on CT,and isointensity on T 1WI and homogeneous hyperintensity on T 2WI.All tumors showed hypertensity on DWI with average ADC value of(0.54±0.11)×10-3 mm 2/s.Conclusion:SCNECC mostly appear as endogenous mass and heterogeneous enhancement,with mild to moderate enhancement on CT,isointensity on T 1WI and slightly homogeneous hyperintensity on T 2WI and restricted diffusion on DWI.

关 键 词：宫颈肿瘤 宫颈小细胞神经内分泌癌 体层摄影术 X线计算机 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R814.42[医药卫生—诊断学] R737.33[医药卫生—临床医学]