112例新发现HIV/AIDS病例首次CD4+T淋巴细胞检测结果的分析  

Analysis of the first CD4+T lymphocyte detection results in 112 newly discovered HIV/AIDS cases

作　　者：蒋艳凤[1] 伍丽娜 蒋叶伟 谢晏婷 JIANG Yanfeng;WU Lina;JIANG Yewei;XIE Yanting(Quanzhou Center for Disease Control and Prevention,GuilinGuangxi541500)

机构地区：[1]全州县疾病预防控制中心,广西桂林541500

出　　处：《当代医药论丛》2023年第5期134-137,共4页

摘　　要：目的:分析全州县2019年至2021年新发现艾滋病病毒(HIV)/艾滋病(AIDS)病例当年的首次CD4+T淋巴细胞(简称CD4细胞)检测情况及其影响因素,为探索符合当地实际情况的精准防控防治措施提供科学依据。方法:从全州县疾控中心“艾滋病防治基本信息系统”中下载2019年1月至2021年12月新报告的本地户籍未进行抗病毒治疗,且当年进行首次CD4细胞检测的HIV/AIDS病例的AIDS病例报告卡、随访表,应用SPSS17.0软件包和Excel2007对数据进行统计分析,计数资料以率或构成比表示,将人口学特征和感染途径纳入统计变量,两组间比较用t检验,多组间比较用方差分析,明确CD4细胞的检测结果及其影响因素。结果:本研究中首次检测CD4细胞的HIV/AIDS病例共112例,其中男性72例(占64.29%),女性40例(占35.71%)。2019年、2020年和2021年确诊的本地户籍HIV/AIDS病例分别有39例、39例和49例,当年首次检测CD4细胞的病例数分别为29例(74.36%)、36例(92.31%)、47例(95.91%),CD4细胞计数值最小为4个/μL,最大为731个/μL,均值为(286.26±194.39)个/μL。不同年龄、职业HIV/AIDS病例当年的首次CD4细胞检测结果比较差异有统计学意义(P<0.05)。结论:全州县HIV/AIDS病例CD4细胞的检测及时率逐年提高,本县实施新的AIDS检测策略收效显著,重点加强农村中老年人的AIDS防控工作,创新不同防控模式,尽量做到早发现、早治疗。Objective:To analyze the first detection of CD4+T lymphocytes(referred to as CD4 cells)in newly discovered HIV/AIDS cases in Quanzhou County from 2019 to 2021 and its influencing factors,so as to provide scientific basis for exploring precise prevention and control measures in line with the local situation.Method:Download the AIDS case report card and follow-up form of HIV/AIDS cases newly reported from January 2019 to December 2021 who have not received antiviral treatment and have had their first CD4 cell test in the same year from the“AIDS Prevention and Control Basic Information System”of Quanzhou County CDC.SPSS17.0 software package and Excel2007 were used for statistical analysis of the data.The count data were expressed as rate or component ratio,and the demographic characteristics and infection route were included as statistical variables.T-test was used for comparison between two groups,and analysis of variance was used for comparison between multiple groups,so as to clarify the detection results of CD4 cells and its influencing factors.Results:In this study,a total of 112 HIV/AIDS cases with CD4 cells were detected for the first time,including 72 males(64.29%)and 40 females(35.71%).There were 39,39 and 49 cases of HIV/AIDS diagnosed in 2019,2020 and 2021,respectively.In that year,the number of CD4 cells detected for the first time was 29(74.36%),36(92.31%)and 47(95.91%),and the minimum count of CD4 cells was 4/μL.The maximum was 731/μL,and the mean was(286.26±194.39)/μL.There were significant differences in the results of first CD4 cell detection among HIV/AIDS patients of different ages and occupations(P<0.05).Conclusions:The timely detection rate of CD4 cells in HIV/AIDS cases in Quanzhou County increased year by year,and the implementation of new AIDS detection strategy in Quanzhou County achieved significant results.It is important to strengthen AIDS prevention and control work in rural middle aged and elderly people,innovate different prevention and control modes,and try to achieve early de

关 键 词：艾滋病病毒 艾滋病 CD4+T细胞 影响因素 

分 类 号：R512.91[医药卫生—内科学]