血培养延时报警病原菌分布及特征分析  

Distribution and characteristic analysis of pathogenic bacteria with delayed alarm in blood culture

作　　者：向宇培 古丽 许迅 XIANG Yupei;GU Li;XU Xun(Department of Clinical Laboratory,Jiulongpo District People′s Hospital,Chongqing 400050,China)

机构地区：[1]重庆市九龙坡区人民医院检验科,重庆400050

出　　处：《现代医药卫生》2023年第5期786-788,793,共4页Journal of Modern Medicine & Health

基　　金：重庆市九龙坡区科技计划项目(2021-02-014-Y)。

摘　　要：目的探讨血培养延时(>5 d)报警的阳性率、病原菌分布及报警时间特征,为完善临床实验室血培养检测方案提供数据。方法统计九龙坡区人民医院2019年6月至2021年6月血培养标本7576例,将常规时间(5 d)血培养阴性的标本6866例延长培养到10 d,记录延时报警的阳性率及报警时间,并统计病原菌的种类及构成。结果常规时间血培养阳性率为9.4%,10 d培养阳性率为9.8%,两者比较,差异无统计学意义(P>0.05);延时报警血培养标本36例,占常规阳性标本的5.1%。共分离细菌37例,其中污染菌7例,污染率为18.9%。36例延时报警标本中,报警时间最短为5.2 d,最长为10.0 d,报警时间中位数7.1 d。结论延长培养时间不能够显著提高血培养的阳性率,但可以提高少见菌的检出率。Objective To investigate the positive rate,the distribution of pathogenic bacteria and the characteristics of alarm time of delayed blood culture(more than five day)alarm,so as to provide data for improving the blood culture detection scheme in clinical laboratory.Methods A total of 7576 blood culture samples were collected from Jiulongpo District People′s Hospital from June 2019 to June 2021,and 6866 negative blood culture samples for routine time(five days)were cultured for 10 days.The positive rate and alarm time of delayed alarm were recorded,and the species and composition of the pathogenic bacteria were counted.Results The positive rate of blood culture in routine time was 9.4%,and that at 10 days was 9.8%.There was no significant difference between the two groups(P>0.05).The delayed blood culture samples were reported in 36 cases,accounting for 5.1%of the conventional positive samples.A total of 37 bacteria were isolated,among which seven were contaminated,with a contamination rate of 18.9%.Among the 36 delayed alarm specimens,the shortest alarm time was 5.2 days,the longest was 10.0 days,and the median alarm time was 7.1 days.Conclusion Prolonging culture time can not significantly improve the positive rate of blood culture,but can improve the detection rate of rare bacteria.

关 键 词：血培养 报警时间 阳性率 污染率 

分 类 号：R446.5[医药卫生—诊断学]