免疫分析芯片检测系统设计与实验  

Design and experiment of detection system for immunoassay chip

作　　者：徐铁 涂亚庆 牟泽龙 刘晓竹 XU Tie;TU Yaqing;MOU Zelong;LIU Xiaozhu(Unit 61150 of PLA,Yulin 719000,China;Department of Military Logistics,Army Logistics University,Chongqing 401311,China;Chongqing Weiaoyun Biotechnology Co Ltd,Chongqing 400039,China)

机构地区：[1]中国人民解放军61150部队,陕西榆林719000 [2]陆军勤务学院军事物流系,重庆401311 [3]重庆微奥云生物技术有限公司,重庆400039

出　　处：《传感器与微系统》2023年第3期84-86,90,共4页Transducer and Microsystem Technologies

基　　金：国家重大专项项目(2018YBF2003905);国家自然科学基金资助项目(61271449,61871402);重庆市自然科学重点基金资助项目(CSTC2015JCYJBX0017,CSTC2019JCYJ-MSXMX0245)。

摘　　要：免疫分析芯片技术具有易控、消耗少、速度快等优点,一般需要专业人员在大型、昂贵、耗时且操作复杂的仪器上完成。本文开发一种快速、低成本的免疫分析芯片复阻抗检测系统,以单片机(MCU)和现场可编程门阵列(FPGA)为硬件核心,以复数计算模型为软件核心,对双ADC误差与寄生电感误差进行矫正。实验表明:检测免疫分析芯片复阻抗可在4 min内完成,可达0.1%的幅值误差及0.2°相位误差。The immunoassay chip technology has the advantages of easy control, low consumption, and high speed, which generally requires professionals to complete on a large, expensive, time-consuming and complex operation instrument.A fast and low-cost immune analysis chip is developed with complex impedance detection system, which uses MCU and FPGA as the hardware core and complex calculation model as the software core to correct the dual ADC error and parasitic inductance error.Experiments show that the detection of the complex impedance of the immunoassay chip can be completed within 4 minutes, with an amplitude error of 0.1 % and a phase error of 0.2°.

关 键 词：复阻抗 检测系统 单片机 现场可编程门阵列 免疫分析芯片 

分 类 号：TP29[自动化与计算机技术—检测技术与自动化装置]