老年性骨质疏松性疼痛的研究进展  

Research progress about senile osteoporotic pain

作　　者：沈茂荣 谢斌 吴卓霏 张辉宇 SHEN Maorong;XIE Bin;WU Zhuofei(Guangxi Orhopaedic Traumatology Hospital,Guangxi,Nanning 530000,China;不详)

机构地区：[1]广西骨伤医院,南宁市530000 [2]广西中医药大学

出　　处：《河北医药》2023年第1期114-118,124,共6页Hebei Medical Journal

基　　金：广西医疗卫生适宜技术开发与推广应用项目基金资助(编号:S2019506)。

摘　　要：随着我国人口老龄化问题的愈加严重,老年性骨质疏松症(senile osteoporosis,SOP)患者日趋增多。除了脆性骨折,SOP性骨痛也极大影响老年人的生活质量。非骨折性疼痛与传统的骨折源性疼痛不同,称为老年性骨质疏松性疼痛(senile osteoporosis pain,SOPP),可能与骨吸收、炎症刺激、神经病理改变、中枢致敏、肌肉痉挛、情感认知等方面有关。针对目前临床一般的疼痛疗法疗效不佳的困境,本文从SOPP的发病机制、临床治疗及研究动态等方面进行综述,以期为SOPP的规范化治疗提供新的思路。With the increasingly serious problem of population aging in China, the number of patients with senile osteoporosis(SOP) is increasing.In addition to brittle fractures, SOP induced bone pain also greatly affects the life quality of elderly patients.This kind of non fracture pain, different from the traditional fracture induced pain, is called senile osteoporosis pain(SOPP),which may be related to bone resorption, inflammatory stimulation, neuropathological changes, central sensitization, muscle spasm, emotional cognition..In view of the poor efficacy of general clinical pain therapy, this article attempts to review the pathogenesis, clinical treatment and research trends of SOPP,so as to provide new ideas for the standardized treatment of SOPP.

关 键 词：老年性骨质疏松性疼痛 机制 治疗 综述 

分 类 号：R441.1[医药卫生—诊断学]