血浆致动脉硬化指数及动态动脉硬化指数与冠心病SYNTAX评分的相关性分析  

Correlation analysis between atherogenic index of plasma,ambulatory arterial stiffness index and SYNTAX score in patients with coronary heart disease

作　　者：胡婧 江小杰[1] 衷涛 何涛 李顺辉[1] HU Jing;JIANG Xiao-jie;ZHONG Tao(Nanchang First Hospital,Nanchang 330006,China)

机构地区：[1]江西南昌市第一医院,330006

出　　处：《中国实用医药》2023年第3期14-17,共4页China Practical Medicine

基　　金：江西省卫生健康委科技计划(项目编号:20204003),项目名称:冠心病血浆致及动态动脉硬化指数与SYNTAX评分的相关性分析。

摘　　要：目的探讨血浆致动脉硬化指数(AIP)及动态动脉硬化指数(AASI)与冠心病心脏外科与介入治疗狭窄冠状动脉研究(SYNTAX)评分的相关性。方法100例冠心病患者,根据冠状动脉造影结果进行SYNTAX评分,根据评分结果将患者分为低分组(≤22分,39例)、中分组(23~32分,41例)及高分组(≥33分,20例)。比较三组AIP、AASI、脂质代谢指标[甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]、空腹血糖(FBG)、肝肾功能[血肌酐(Scr)、天门冬氨酸氨基转移酶(AST)]。采用Pearson检验分析AIP、AASI与SYNTAX评分的相关性,采用Logistic回归模型分析冠心病患者SYNTAX评分的影响因素。结果高分组患者的AIP、AASI、LDL-C均高于中分组和低分组,HDL-C低于中分组和低分组,差异有统计学意义(P<0.05)。三组患者的TG、TC、FBG、Scr及AST水平比较差异无统计学意义(P>0.05)。Pearson相关分析显示,AIP、AASI与SYNTAX评分均呈正相关(r=0.620、0.557,P<0.05)。Logistic回归分析结果显示,高血压、高血脂、未服用抗血小板药物、AIP、AASI、HDL-C是SYNTAX评分的影响因素(OR>1,P<0.05)。结论AIP、AASI与冠心病患者SYNTAX评分密切相关,可作为评估患者冠状动脉病变程度的有效指标。Objective To discuss the correlation between atherogenic index of plasma(AIP),ambulatory arterial stiffness index(AASI)and synergy between percutaneous coronary intervention with taxus and cardic surgery(SYNTAX)score in patients with coronary heart disease.Methods 100 patients with coronary heart disease all received coronary angiography,and the results were scored by SYNTAX.According to the scoring results,the patients were divided into low score group(≤22 points,39 cases),medium score group(23-32 points,41 cases)and high score group(≥33 points,20 cases).The AIP,AASI,lipid metabolism indexes[triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C)],fasting blood glucose(FBG),liver and kidney function[serum creatinine(Scr),aspartate aminotransferase(AST)]of the three groups were compared.Pearson test was used to analyze the correlation between AIP,AASI and SYNTAX score,and Logistic regression was used to analyze the influencing factors of SYNTAX score in patients with coronary heart disease.Results The AIP,AASI,LDL-C of patients in the high score group were higher than those in the middle score group and low score group;the HDL-C in the high score group was lower than that in the middle score group and low score group;the differences were statistically significant(P<0.05).There was no statistically significant difference in the levels of TG,TC,FBG,Scr and AST among the three groups(P>0.05).Pearson correlation analysis showed that AIP,AASI and SYNTAX scores were positively correlated(r=0.620,0.557;P<0.05).Logistic regression analysis showed that hypertension,hyperlipidemia,not taking antiplatelet drugs,AIP,AASI,HDL-C were the influencing factors of SYNTAX score(OR>1,P<0.05).Conclusion AIP and AASI are closely related to the SYNTAX score of patients with coronary heart disease,and can be used as an effective index to evaluate the degree of coronary artery disease.

关 键 词：冠心病 血浆致动脉硬化指数 动态动脉硬化指数 心脏外科与介入治疗狭窄冠状动脉研究评分 相关性 

分 类 号：R541.4[医药卫生—心血管疾病]