创伤性肠破裂患者术后急性肺损伤的影响因素分析  

Analysis of Influencing Factors of Postoperative Acute Lung Injury in Patients with Traumatic Enterorrhexis

作　　者：邓丹东 文新元[1] 刘苏 肖斌 宋庚荣 林夕 DENG Dandong;WEN Xinyuan;LIU Su;XIAO Bin;SONG Gengrong;LIN Xi(Pingxiang People's Hospital,Jiangxi Province,Pingxiang 337000,China;不详)

机构地区：[1]江西省萍乡市人民医院,江西萍乡337000

出　　处：《中国医学创新》2023年第5期119-122,共4页Medical Innovation of China

摘　　要：目的:探讨创伤性肠破裂(TE)患者术后出现急性肺损伤(ALI)的影响因素。方法:回顾性分析2019年1月-2021年12月萍乡市人民医院收治的92例TE患者的临床资料,按术后是否发生ALI将患者分为ALI组(n=19)与非ALI组(n=73)。采取logistic回归分析ALI发生的影响因素。结果:ALI组的外周血降钙素原(PCT)、人表面活性蛋白D(SP-D)、肺表面活性物质相关蛋白A(SP-A)、白细胞介素-1β(IL-1β)、肺损伤评分(LIS)、肺损伤预测评分(LIPS)均高于非ALI组(P<0.05)。logistic回归分析显示SP-D、SP-A、IL-1β水平是ALI发生的危险因素(P<0.05)。结论:SP-D、SP-A、IL-1β检测结果与TE患者术后发生ALI之间有着密切关联,LIS、LIPS评分在早期识别ALI的发生方面有重要价值,可考虑与实验室指标检测结果相结合,构建ALI风险预测模型。Objective:To investigate the influencing factors of postoperative acute lung injury(ALI)in patients with traumatic enterorrhexis(TE).Method:The clinical data of 92 patients with TE admitted to Pingxiang People’s Hospital from January 2019 to December 2021 were retrospectively analyzed,and the patients were divided into ALI group(n=19)and non-ALI group(n=73)according to the occurrence of postoperative ALI.The influencing factors of ALI were analyzed by logistic regression.Result:Peripheral blood calcitoninogen(PCT),human surface active protein D(SP-D),pulmonary surfactant-associated proteins A(SP-A),interleukin-1β(IL-1β),lung injury score(LIS),and lung injury prediction score(LIPS)in the ALI group were higher than those in the non-ALI group(P<0.05).logistic regression analysis showed that the levels of SP-D,SP-A and IL-1βwere risk factors for ALI(P<0.05).Conclusion:There is a close association between SP-D,SP-A,and IL-1βtest results and the occurrence of ALI in TE patients after surgery,and the LIS and LIPS scores have important values in the early identification of the occurrence of ALI,which can be considered in combination with laboratory index test results to construct a prediction model for ALI risk.

关 键 词：创伤性肠破裂 急性肺损伤 风险预测 

分 类 号：R563.8[医药卫生—呼吸系统] R656[医药卫生—内科学]