超早期干预对高危儿神经系统发育的临床疗效研究  

Clinical Effect of Ultra-early Intervention on Nervous System Development in High-risk Infants

作　　者：曾远 宋欢欢 赖轻 刘琦赟 孟丽娟 ZENG Yuan;SONG Huanhuan;LAI Qing;LIU Qiyun;MENG Lijuan(Pingxiang Maternity and Child Care,Jiangxi Province,Pingxiang 337000,China;不详)

机构地区：[1]江西省萍乡市妇幼保健院,江西萍乡337000

出　　处：《中国医学创新》2023年第7期84-88,共5页Medical Innovation of China

基　　金：江西省卫生健康委科技计划项目(SKJP220219337)。

摘　　要：目的:探讨综合性的超早期干预技术对高危儿神经系统发育的临床疗效。方法:选取2021年1-6月萍乡市妇幼保健院新生儿科收治的符合高危儿诊断的新生儿90例,将患儿随机分为对照组、干预1组和干预2组,各30例。对照组给予常规护理干预,干预1组在对照组基础上给予视听觉、触觉训练,干预2组在干预1组基础上给予口腔功能、运动感知觉功能、心肺功能、袋鼠式护理等综合性的超早期干预。记录并对比三组新生儿神经行为测定(NBNA)评分、全身运动(GMs)质量评估、Peabody运动发育量表-2的总运动发育商(TMQ)。观察并统计实施超早期干预技术过程中的不良反应和不良事件,探讨其用于临床治疗的安全性。结果:三组28日龄时NBNA评分、3月龄时GMs异常率、8月龄和12月龄时TMQ比较,差异均有统计学意义(P<0.05),且干预2组的NBNA评分、TMQ均明显优于其余两组,干预2组GMs异常率明显低于对照组(P<0.05)。超早期干预过程中,对照组和干预1组各有1例过敏反应,无不良事件发生。结论:综合性的超早期干预技术能更有效地促进高危儿神经系统的发育,且其用于临床具有较高的安全性。Objective:To explore the clinical effect of comprehensive ultra-early intervention technology on nervous system development of high-risk infants.Method:A total of 90 newborns diagnosed as high-risk infants in the Department of Newborn,Pingxiang Maternity and Child Care from January to June 2021 were selected and randomly divided into the control group,intervention 1 group and intervention 2 group,with 30 cases in each group.The control group was given routine nursing intervention,the intervention 1 group was given audio-visual and tactile training on the basis of the control group,and the intervention 2 group was given comprehensive ultra-early intervention such as oral function,motor perception function,cardiopulmonary function and kangaroo nursing on the basis of the intervention 1 group.The neonatal behavioral neurological assessment(NBNA)scores,the quality evaluation of general movements(GMs)and the total motor developmental quotient(TMQ)of Peabody developmental motor scales-2 were recorded and compared among the three groups.The adverse reactions and events during the implementation of ultra-early intervention technology were observed and counted,and the safety of its clinical treatment was explored.Result:Comparison of NBNA scores at 28 days of age,abnormal rates of GMs at 3 months of age,TMQ at 8 and 12 months of age among the three groups,the differences were statistically significant(P<0.05),and the NBNA scores and TMQ in the intervention 2 group were significantly better than those in the other two groups,and the abnormal rate of GMs in the intervention 2 group was significantly lower than that in the control group(P<0.05).During the ultra-early intervention,there was one allergic reaction in the control group and one in the intervention 1 group,and no adverse events occurred.Conclusion:Comprehensive ultra-early intervention technology can more effectively promote the development of nervous system in high-risk infants,and it has high safety for clinical use.

关 键 词：超早期干预 高危儿 新生儿 神经系统发育 新生儿神经行为测定 全身运动 

分 类 号：R473.72[医药卫生—护理学]