门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死室性心律失常的疗效分析  

Efficacy analysis of potassium magnesium aspartate combined with amiodarone on ventricular arrhythmia in patients with acute myocardial infarction

作　　者：邵丹丹 SHAO Dan-dan(Department of Cardiology,People's Hospital of Shenyang Economic and Technological Development Zone,Shenyang 110000,China)

机构地区：[1]沈阳经济技术开发区人民医院心内科,110000

出　　处：《中国现代药物应用》2023年第4期110-112,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨门冬氨酸钾镁联合胺碘酮治疗急性心肌梗死(AMI)室性心律失常的临床疗效。方法88例AMI室性心律失常患者为研究对象,依据治疗方法不同分为观察组与对照组,各44例。对照组采用胺碘酮治疗,观察组采用门冬氨酸钾镁联合胺碘酮治疗。对比两组治疗效果、治疗前后心功能[每搏输出量(SV)、左心室收缩压(LVSP)、左心室射血分数(LVEF)]水平。结果观察组治疗总有效率95.45%高于对照组的79.55%,差异有统计学意义(P<0.05)。治疗后,观察组SV(70.17±6.38)ml、LVSP(87.28±5.35)mm Hg(1 mm Hg=0.133 kPa)、LVEF(56.22±6.15)%均高于对照组的(65.19±6.72)ml、(82.07±5.51)mm Hg、(51.78±6.19)%,差异均有统计学意义(P<0.05)。结论门冬氨酸钾镁联合胺碘酮治疗AMI室性心律失常,可以有效改善患者心功能,效果显著,安全可靠。Objective To discuss the clinical efficacy of potassium magnesium aspartate combined with amiodarone on ventricular arrhythmia in patients with acute myocardial infarction(AMI).Methods A total of 88 patients with ventricular arrhythmia after acute myocardial infarction were studied,and the patients were divided into observation group and control group based on different treatment methods,with 44 cases in each group.The control group was treated with amiodarone,and the observation group was treated with potassium magnesium aspartate and amiodarone.Both groups were compared in terms of therapeutic effect,cardiac function[stroke volume(SV),left ventricular systolic pressure(LVSP),left ventricular ejection fraction(LVEF)]levels before and after treatment.Results The total effective rate of treatment in the observation group was 95.45%,which was higher than 79.55%in the control group,and the difference was statistically significant(P<0.05).After treatment,the SV(70.17±6.38)ml,LVSP(87.28±5.35)mm Hg(1 mm Hg=0.133 kPa)and LVEF(56.22±6.15)%in the observation group were higher than(65.19±6.72)ml,(82.07±5.51)mm Hg and(51.78±6.19)%in the control group,and the differences were statistically significant(P<0.05).Conclusion Potassium magnesium aspartate combined with amiodarone in the treatment of ventricular arrhythmia has significant effect in patients with acute myocardial infarction,and can effectively improve the cardiac function of patients,and it is safe and reliable.

关 键 词：门冬氨酸钾镁 胺碘酮 急性心肌梗死 室性心律失常 价值 

分 类 号：R541.7[医药卫生—心血管疾病] R542.22[医药卫生—内科学]