国产体外膜氧合设备的研发现状和应用前景  

Research,development status and application prospects of domestic extracorpo⁃real membrane oxygenation devices

作　　者：任明仕 董士勇 申华 王嵘[1] Ren Mingshi;Dong Shiyong;Shen Hua;Wang Rong(Department of Adult Cardiac Surgery,Sixth Medical Center,Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院第六医学中心心血管病医学部成人心脏外科,北京100853 [2]解放军医学院,北京100853

出　　处：《中国体外循环杂志》2022年第6期365-370,共6页Chinese Journal of Extracorporeal Circulation

摘　　要：体外膜氧合(ECMO)技术,作为一种可经皮置入的机械循环辅助技术,具有置入方便、不受地点限制、可同时提供心肺功能支持等优点,越来越多地被应用于常规生命支持无效的各种急性循环和/或呼吸衰竭。在我国,尽管近年来ECMO技术得到了快速的应用和发展,但相关设备及耗材仍完全依赖进口,费用高昂,显著增加了患者及国家医疗支付体系的负担。尽快推动ECMO国产化,不仅能够解决我国在关键高端医疗装备方面的“卡脖子”问题,而且有望推进ECMO临床应用规模、大幅降低使用费用,让更多患者受益。国内一些企业致力于ECMO设备国产化多年,已经在部分领域取得突破,如小型集成化主机、改良离心泵等方面的研发。本文将就国内ECMO技术开展现状、国产化ECMO设备的临床需求及应用前景、国产化ECMO设备及耗材的研发现状以及国产化ECMO研发面临的机遇及挑战进行综述,以期为ECMO设备及耗材的国产化研发与应用提供借鉴。Extracorporeal membrane oxygenation(ECMO)technology is increasingly used in acute circulatory and/or respir⁃atory failure where conventional life support is ineffective,as a percutaneous mechanical circulatory assist technique which is easy to place,location-independent,and can provide simultaneous biventricular and respiratory assistance.In China,although ECMO technol⁃ogy has been rapidly applied and developed in recent years,related equipment and consumables are still completely dependent on im⁃ports with high costs,which significantly increases the burden of patients and the national medical payment system.Promoting the local⁃ization of ECMO as soon as possible can not only solve the key problem in high-end medical equipment in China,but is also expected to promote the scale of clinical application of ECMO,significantly reduce the cost,and benefit more patients.Some domestic enterpri⁃ses have been committed to the localization of ECMO equipment for many years and have made some breakthrough in some fields,such as the research and development of small integrated mainframes,modified centrifugal pumps,etc.This paper will review the current sit⁃uation of ECMO technology development,R&D of localized ECMO devices and consumables in China,the clinical demand and applica⁃tion prospect of localized ECMO devices,and the opportunities and challenges,in order to provide reference for the R&D and applica⁃tion of localized ECMO devices and consumables.

关 键 词：体外膜氧合 体外生命支持 膜式氧合器 离心泵 国产化设备 

分 类 号：R197.39[医药卫生—卫生事业管理]