荧光染色法与复方氢氧化钾湿片法在1025例皮肤浅部真菌感染检测中的比较  

Comparision of fluorescent staining and KOH wet-mount in detecting superficial fungal infection from 1025 patients

作　　者：王捷敏 龙宾曼 刘琼[1] 许贵霞 张思平 WANG Jiemin;LONG Binman;LIU Qiong;XU Guixia;ZHANG Siping(Department of Dermatology,The First Affiliated Hospital of USTC,Hefei,Anhui 230001,China)

机构地区：[1]中国科学技术大学附属第一医院皮肤科,安徽合肥230001

出　　处：《安徽医药》2023年第4期808-810,I0002,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的比较荧光染色法与复方氢氧化钾(KOH)湿片法在浅部真菌感染中的应用效果。方法对2019年9月至2020年9月就诊于中国科学技术大学附属第一医院的1025例拟诊为浅表皮肤真菌感染的病人,分别进行荧光染色和KOH湿片镜检,比较两种检测方法阳性率有无差异。结果荧光染色法与KOH湿片法检测1025例浅部真菌感染病人的阳性率分别为82.93%和68.88%,差异有统计学意义(χ^(2)=55.30,P<0.001)。结论荧光染色法相比于KOH湿片法更敏感、准确,是临床浅部真菌感染快速有效的辅助诊断方法。Objective To compare the application of fluorescent staining and KOH wet-mount in superficial fungal infection.Methods A total of 1025 samples from suspected superficial fungal infection patients who were treated in The First Affiliated Hospital of USTC from September 2019 to September 2020 were simultaneously detected by fluorescence staining and KOH wet-mount,then the positive rate of the two methods were compared.Results The total positive rate of 1025 samples by the fluorescent staining,KOH wet-mount were 82.93%and 68.88%,respectively.There was a significant difference between the two methods(χ^(2)=55.30,P<0.001).Conclusion Fluorescent staining is more sensitive and accurate than KOH wet-mount,which can be used in detecting of superficial fungal infection.

关 键 词：真菌病 荧光染色 氢氧化钾湿片法 浅部真菌感染 皮肤 诊断 

分 类 号：R756[医药卫生—皮肤病学与性病学]