自体皮肤移植的临床研究进展  

Clinical progress of the autologous skin grafting

作　　者：何爱娟 叶信海 HE Aijuan;YE Xinhai(Department of Facial Plastic and Reconstructive Surgery,Eye&ENT Hospital,Fudan University,Shanghai 200031,China)

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼耳鼻整形外科,上海200031

出　　处：《中国眼耳鼻喉科杂志》2023年第2期123-127,共5页Chinese Journal of Ophthalmology and Otorhinolaryngology

摘　　要：皮肤是人类抵御外部伤害的第一道防线。如何有效修复皮肤缺损以重建皮肤屏障、恢复功能是重建外科学的研究重点。自体皮肤移植是大面积皮肤缺损修复的金标准。然而,组织来源有限、获取供区缺损、皮片存活不良、色素沉着等问题一直是自体皮肤移植面临的难题。本文重点综述目前自体皮肤移植的新方法、影响移植皮片成活率的因素及改善措施、植皮后色素沉着的治疗策略等方面,为自体皮肤移植的后续研究方向提供参考。The skin is the first line of defense against harmful influences for human.How to effectively repair tissue defect and reconstruct the skin barrier remain important issues for reconstructive surgery.To date,autologous skin grafting is commonly considered as the gold standard for the coverage of large skin defects.However,limited tissue source,donor site-availability,skin necrosis,and hyperpigmentation problems continue to be major clinical challenge.This study aims to review the new technologies of autologous skin grafting,factors associated with skin graft take rate and measures for improving the survival rate of skin grafts,the pathological change and treatment strategies for pigmentation of skin graft,so as to provide insight for future research of autologous skin graft.

关 键 词：皮肤移植 皮片坏死 辅助负压封闭 色素沉着 

分 类 号：R622[医药卫生—整形外科]