PRO-BNP、FMD、6MWT、出院运动指导对慢性心衰患者30天再入院的影响  

Effects of PRO-BNP,FMD,6MWT and discharge exercise guidance on 30-day readmission in patients with chronic heart failure

作　　者：张伶俐[1] 陈楠[1] 冯菊凤 Zhang Lingli;Chen Nan;Feng Jufeng(Department of Cardiovascular Medicine,Yuebei People's Hospital Shaoguan City,Shaoguan,Guangdong 512025,China)

机构地区：[1]广东省韶关市粤北人民医院,广东韶关512025

出　　处：《首都食品与医药》2023年第4期11-13,共3页Capital Food Medicine

基　　金：2021年韶关市卫生健康科研计划项目(项目编号:Y21255)。

摘　　要：目的 探讨B型脑钠肽前体(PRO-BNP)、肱动脉内皮依赖性舒张功能(FMD)、6分钟步行试验(6MWT)、出院运动指导对慢性心衰(CHF)患者30天再入院的影响.方法 回顾性分析2020年11月-2022年3月韶关市粤北人民医院收治的共计40例CHF患者的临床资料,根据患者是否为30天再入院分组,并进行单因素分析与Logistic多因素回归分析.结果 40例CHF患者中,10例(25.00%)为30天再入院患者,30例(75.00%)为非30天再入院患者;再入院组食盐量、PRO-BNP水平较非再入院组明显更高(P<0.05),FMD、出院运动指导占比明显更低(P<0.05),6MWT明显更短(P<0.05);Logistic多因素回归分析结果显示,PRO-BNP(OR=2.164)是影响CHF患者30天再入院的独立危险因素(P<0.05),FMD(OR=0.536)、6MWT(OR=0.560)、出院运动指导(OR=0.575)是影响CHF患者30天再入院的保护性因素(P<0.05).结论 CHF患者30天再入院受到多种因素的影响,包括PRO-BNP、FMD、6MWT等,应积极对危险因素进行控制,出院运动指导可降低30天再入院率,应积极提倡,以降低再入院率.Objective To investigate the effects of B-type brain natriuretic peptide precursor(PRO-BNP),brachial artery endotheliumdependent diastolic function(FMD),6-minute walking test(6MWT)and discharge exercise instruction on 30-day readmission in patients with chronic heart failure(CHF).Methods A retrospective analysis in November 2020 to March 2022,our hospital the clinical data of a total of 40 patients with CHF,grouping reentry according to whether patients for 30 days,and factor of single factor analysis and Logistic regression analysis.Results Among the 40 CHF patients,10(25.00%)were readmitted at 30 days,and 30(75.00%)were not readmitted at 30 days.Compared with non-readmission group,salt intake and PRO-BNP levels were significantly higher in readmission group(P<0.05),the proportion of FMD and discharge exercise guidance was significantly lower(P<0.05),and 6MWT was significantly shorter(P<0.05).Logistic multifactor regression analysis showed that PRO-BNP(OR=2.164)was independent risk factors for 30-day readmitted CHF patients(P<0.05).FMD(OR=0.536)and 6MWT(OR=0.560),discharge exercise instruction(OR=0.575)were a protective factor affecting 30-day readmission in CHF patients(P<0.05).Conclusions 30-day readmission of CHF patients is affected by a variety of factors,including PRO-BNP,FMD,6MWT,etc.Risk factors should be actively controlled,discharge exercise guidance can reduce the 30 day readmission rate,and should be actively advocated to reduce the readmission rate.

关 键 词：B型脑钠肽前体 肱动脉内皮依赖性舒张功能 6分钟步行试验 出院运动指导 慢性心衰 30天再入院 

分 类 号：R541.6[医药卫生—心血管疾病]