胰岛素联合平衡盐溶液对老年重度糖尿病酮症酸中毒患者β2微球蛋白、FT4水平的影响  

Effects of insulin combined with balanced salt solution on levels of β2-microglobulin and FT4 in elderly patients with severe diabetic ketoacidosis

作　　者：单秋妹 于宏[1] Shan Qiumei;Yu Hong(Tianjin Wuqing District People's Hospital,Tianjin 301700,China)

机构地区：[1]天津市武清区人民医院,天津301700

出　　处：《首都食品与医药》2023年第4期71-73,共3页Capital Food Medicine

摘　　要：目的 分析在为老年重度糖尿病酮症酸中毒(Diabetic ketoacidosis,DKA)患者实施治疗过程中胰岛素联合平衡盐溶液对其β2微球蛋白与FT4水平造成的影响.方法 此研究选取2021年1月-12月收治的老年重度DKA患者78例为研究对象,按照随机数字表法将其分为试验组与对比组,其中试验组39例患者的治疗方法为胰岛素联合平衡盐溶液,对比组患者的治疗方法为胰岛素联合生理盐水.结果 试验组患者治疗效果显著优于对比组患者,P<0.05.治疗前两组患者临床指标、血清指标与电解质指标均无显著差异,P>0.05,治疗后试验组患者显著差别于对比组患者,P<0.05.结论 对于老年重度DKA患者来说,胰岛素联合平衡盐溶液是一种相对较为理想的治疗方式,对患者β2微球蛋白、FT4等血清指标、电解质与临床指标均有显著影响.Objective To analyze the effects of insulin combined with balanced salt solution on the levels ofβ2-microglobulin and FT4 in elderly patients with severe Diabetic ketoacidosis ketoacidosis(DKA).Methods A total of 78 elderly patients with severe DKA from January to December of the 2021 were randomly divided into trial group and control group,among them,39 patients in test group were treated with insulin combined with balanced salt solution,and the other 39 patients in control group were treated with insulin combined with normal saline.Results The results showed that the therapeutic effect of the experimental group was significantly better than that of the control group(P<0.05).Before treatment,there were no significant differences in clinical indexes,serum indexes and electrolyte indexes between the two groups,P>0.05;after treatment,there were significant differences between the trial group and the control group,P<0.05.Conclusion Insulin combined with balanced salt solution is a relatively ideal treatment for elderly patients with severe DKA,the serum levels ofβ2-microglobulin,FT4,electrolytes and clinical parameters were significantly affected.

关 键 词：胰岛素 平衡盐溶液 生理盐水 老年重度糖尿病酮症酸中毒 Β2微球蛋白 FT4 

分 类 号：R587.1[医药卫生—内分泌]