肠道菌群及其代谢物与痛风  

Intestinal Flora and Its Metabolites and Gout

作　　者：卢燕 刘亚萍 罗强 张全波[1,2] 汪汉 LU Yan;LIU Yaping;LUO Qiang;ZHANG Quanbo;WANG Han(North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Cardiology,The Affiliated Hospital of Southwest Jiaotong University,The Third People’s Hospital of Chengdu,Cardiovascular Disease Research Institute of Chengdu,Chengdu 610031,Sichuan,China)

机构地区：[1]川北医学院,四川南充637000 [2]西南交通大学附属医院成都市第三人民医院心内科成都市心血管病研究所,四川成都610031

出　　处：《心血管病学进展》2023年第2期177-180,185,共5页Advances in Cardiovascular Diseases

基　　金：四川省中医药管理局(2020JC0010);成都市卫健委医学科研课题(2021206)。

摘　　要：肠道是人体内最重要的消化器官和排毒器官,而肠道菌群则是一个高度多样化的生态系统,其各种菌群及代谢物之间的相互平衡对于人体的健康至关重要。肠道菌群的种类变化、数量失调、定位转移及其代谢产物等失衡与多种疾病有关。目前关于肠道菌群及代谢物与痛风关系的研究日益成为热点。现通过从肠道菌群及其代谢物概况、痛风患者肠道菌群及其代谢物改变、肠道菌群及其代谢物引起痛风的机制及目前的相关治疗方面进行概述。The gut is the most important digestive organ and detoxification organ in the human body,and the intestinal flora is a highly diverse ecosystem.The mutual balance between them is crucial to human health.Imbalances in the variety,quantity,location transfer and metabolites of intestinal flora are related to a variety of diseases.At present,research on the relationship between intestinal flora and metabolites and gout has become a hot topic.In this paper,the overview of intestinal flora and metabolites,the changes of intestinal flora and metabolites in patients with gout,the mechanism of intestinal flora and metabolites causing gout,and the current related treatments were reviewed.

关 键 词：肠道菌群 肠道代谢产物 痛风 高尿酸血症 

分 类 号：R589.7[医药卫生—内分泌]