股骨近端防旋髓内钉在老年股骨粗隆间骨折中的疗效及对机体创伤应激的控制效果观察  

Effect of Proximal Femoral Antirotation Intramedullary Nail in Elderly Patients with Intertrochanteric Fracture and Influence for Control Effect of Body Traumatic Stress

作　　者：詹兴洪 章国荣 ZHAN Xinghong;ZHANG Guorong(Ningde Municipal Hospital of Ningde Normal University,Ningde 352100,China;不详)

机构地区：[1]宁德师范学院附属宁德市医院,福建宁德352100

出　　处：《中外医学研究》2023年第7期58-62,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究股骨近端防旋髓内钉在老年股骨粗隆间骨折中的疗效及对机体创伤应激的控制效果。方法:选取2019年12月—2021年12月宁德师范学院附属宁德市医院收治的80例老年股骨粗隆间骨折患者,根据随机数表法分为对照组和观察组,各40例。对照组采用股骨近端解剖型锁定钢板进行治疗,观察组则进行股骨近端防旋髓内钉治疗。比较两组术后的髋关节功能优良率、术中出血量、手术时间、下床时间、术后并发症发生率、手术前后的机体创伤应激反应指标[核因子κB(NF-κB)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)前列腺素E_(2)(PGE_(2))、皮质醇(Cor)及血清醛固酮(ALD)]。结果:观察组的髋关节功能优良率显著高于对照组,术中出血量显著少于对照组,手术时间及下床时间显著短于对照组,术后并发症发生率显著低于对照组,差异均有统计学意义(P<0.05)。术前,两组的机体创伤应激反应指标比较,差异无统计学意义(P>0.05);术后1 d、3 d及7 d,两组的机体创伤应激反应指标先升后降,且观察组的检测水平均显著低于对照组,差异有统计学意义(P<0.05)。结论:股骨近端防旋髓内钉在老年股骨粗隆间骨折中的疗效较好,且可有效控制对机体的创伤应激程度。Objective:To investigate the effect of proximal femoral antirotation intramedullary nail in elderly patients with intertrochanteric fracture and influence for control effect of body traumatic stress.Method:A total of 80 elderly patients with intertrochanteric fracture admitted to Ningde Municipal Hospital of Ningde Normal University from December 2019 to December 2021 were divided into control group and observation group by the method of random number table,with 40 cases in each group.The control group was treated with proximal femoral anatomical locking plate,while the observation group was treated with proximal femoral antirotation intramedullary nail.The excellent and good rate of hip joint function,intraoperative blood loss,operation time,time to get out of bed,postoperative complication rate,and body trauma stress response indexes[nuclear factor-κB(NF-κB),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),prostaglandin E_(2)(PGE_(2)),cortisol(Cor)and serum aldolase(ALD)]before and after operation between the two groups were compared.Result:The excellent and good rate of hip joint function in the observation group was significantly higher than that in the control group,the amount of intraoperative bleeding was significantly less than that in the control group,the operation time and the time to get out of bed were significantly shorter than those in the control group,and the incidence of postoperative complications was significantly lower than that in the control group,the differences were statistically significant(P<0.05).Before operation,there were no statistically significant differences between the two groups in the indexes of traumatic stress response(P>0.05);at 1 d,3 d and 7 d after operation,the indexes of body trauma stress reaction in the two groups increased first and then decreased,and the detection level in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The effect of proximal femoral antirotation i

关 键 词：股骨近端防旋髓内钉 老年患者 股骨粗隆间骨折 机体创伤应激 

分 类 号：R687.3[医药卫生—骨科学]