2019—2021年本院266例出生缺陷患儿发生情况及其疾病种类分析  

Monitoring Results and Causes Analysis of 266 cases of Birth Defect in Our Hospital from 2019 to 2021

作　　者：马平红 周丽琴[1] 王智慧[1] MA Pinghong;ZHOU Liqin;WANG Zhihui(Xiangcheng People's Hospital of Suzhou,Suzhou 215131,China;不详)

机构地区：[1]苏州市相城人民医院,江苏苏州215131

出　　处：《中外医学研究》2023年第7期154-158,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析2019—2021年苏州市相城人民医院266例出生缺陷(BD)患儿发生情况及其疾病种类。方法:回顾性分析2019年1月—2021年12月苏州市相城人民医院的分娩情况,并统计期间流产、引产和出生胎儿的BD情况,比较不同年份分娩情况及BD发生率、BD患儿性别及产妇年龄。统计BD患儿的死亡情况,统计死胎、死产及7 d内死亡的胎儿数量,分析并比较排名前5位的BD疾病种类。结果:2019—2021年苏州市相城人民医院总分娩量为6514例,BD患儿266例,总发生率为4.08%(266/6514);2019—2021年BD发生率分别3.60%(103/2864)、4.12%(83/2013)及4.89%(80/1637),整体呈上升趋势,但差异无统计学意义(P>0.05),其中2020—2021年BD发生率增幅明显;2019—2021年,266例BD患儿中,男性占比62.03%(165/266),女性占比37.97%(101/266),男性占比均高于女性,且2019年、2020年及2021年BD患儿中男性占比均高于女性;2019—2021年,266例BD患儿产妇中,年龄≥35岁占比66.17%(176/266),年龄<35岁占比33.83%(90/266),年龄≥35岁产妇占比高于年龄<35岁产妇,且2019年、2020年及2021年BD患儿产妇中,年龄≥35岁产妇占比均高于年龄<35岁产妇;2019—2021年BD患儿总死亡率分别为11.65%,8.43%,6.25%,整体呈下降趋势,但差异无统计学意义(P>0.05),其中2021年BD患儿总死亡率最低;BD患儿排名前5为的疾病种类分别为先天性心脏病、多指/趾、外耳畸形、唇腭裂及眼畸形,2019—2021年该5项疾病种类分别占BD疾病种类的60.19%,54.22%及51.25%,其中先天性心脏病占比最高。结论:2019—2021年本院分娩患儿中BD发生率呈上升趋势,但BD死亡率逐渐降低,医院应根据排名最高的5项BD疾病种类加强健康教育及排畸检查的宣传,以降低BD的发生。Objective:To analyze the monitoring results and causes of 266 cases of birth defect(BD)in Xiangcheng People’s Hospital of Suzhou from 2019 to 2021.Method:A retrospective analysis was performed on the delivery situation in Xiangcheng People’s Hospital of Suzhou City from January 2019 to December 2021,and the statistics of abortion,induced labor and BD of the fetus during the period were counted.The birth status and incidence of BD in different years,as well as the sex of BD fetuses and maternal age were compared.The death of BD fetuses was counted,the number of stillbirths,stillbirths and fetuses that died within 7 days were counted,and the top 5 BD disease types were analyzed and compared.Result:From 2019 to 2021,the total delivery volume of Suzhou Xiangcheng People’s Hospital was 6514 cases,of which 266 cases were children with BD,with a total incidence rate of 4.08%(266/6514).The incidence of BD from 2019 to 2021 was 3.60%(103/2864),4.12%(83/2013)and 4.89%(80/1637),respectively,showing an overall upward trend,but the difference was not statistically significant(P>0.05),among them,the incidence of BD increased significantly from 2020 to 2021.From 2019 to 2021,among 266 children with BD,men accounted for 62.03%(165/266)and women accounted for 37.97%(101/266),and the proportion of men was higher than that of women,and the proportion of males in children with BD in 2019,2020 and 2021 were higher than those of females.From 2019 to 2021,among 266 mothers with BD children,66.17%(176/266)were≥35 years old,and 33.83%(90/266)were aged≥35 years old,in addition,in 2019,2020 and 2021,the proportion of women with BD children aged≥35 years were higher than those of women aged<35 years.From 2019 to 2021,the total mortality rates of children with BD were 11.65%,8.43%,and 6.25%,respectively,showing an overall downward trend,but the difference was not statistically significant(P>0.05),the total mortality rate of children with BD in 2021 was the lowest.The top 5 diseases in children with BD were congenital heart diseas

关 键 词：出生缺陷 监测 围产儿 转归 

分 类 号：R174[医药卫生—妇幼卫生保健]