术后防粘连策略及防粘连材料研究进展  

Research progress of postoperative anti-adhesion strategies and materials

作　　者：池秀云 汪孟姣 黄超 李超婧 王富军[1,2] 王璐[1,2] CHI Xiuyun;WANG Mengjiao;HUANG Chao;LI Chaojing;WANG Fujun;WANG Lu(Key Laboratory of Textile Science&Technology,Ministry of Education,Donghua University,Shanghai 201620,China;College of Textiles,Donghua University,Shanghai 201620,China;Sinopec Shanghai Petrochemical Co.,Ltd.,Shanghai 200336,China)

机构地区：[1]东华大学纺织面料技术教育部重点实验室,上海201620 [2]东华大学纺织学院,上海201620 [3]上海昊海生物科技股份有限公司,上海200336

出　　处：《东华大学学报（自然科学版）》2023年第1期134-142,共9页Journal of Donghua University(Natural Science)

基　　金：上海市青年科技英才扬帆计划(20YF1400800)。

摘　　要：外科及微创介入术后粘连会引起一系列的并发症。为了更全面了解粘连特性,以避免术后粘连对病人带来的心理、生理危害,在分析粘连机理的基础上,结合现存的溶液类、凝胶类以及膜类防粘连产品存在的问题,对防粘连的材料、构建策略进行深入分析,并且对盆腹腔、肌腱、硬膜外粘连的特点以及研究进展及商用产品进行归纳总结。研究表明,通过多种技术手段以结合纤维膜、凝胶及溶液的优势,并负载一定药物,将是防粘连产品的主要发展方向。Adhesion after surgery and minimally invasive intervention can cause a series of complications. In order to have a better understanding of the adhesion characteristics and avoid the psychological and physiological hazards caused by postoperative adhesions, based on a brief introduction of the adhesion mechanism, aiming at the existing problems of solution, gel and membrane adhesions, the materials and construction strategies of anti-adhesion materials were analyzed in depth, and the characteristics of pelvic and abdominal cavity, tendon and epidural adhesion were also analyzed. Research progress and commercial products were summarized. The main development direction of anti-adhesion products is to combine the advantages of fiber membrane, gel and solution with a variety of technical means, and to load certain drugs.

关 键 词：防粘连 盆腹腔 肌腱 硬膜外 

分 类 号：TB303[一般工业技术—材料科学与工程]