基于3D-Slicer软件行CTA重建预测颅内动脉瘤破裂的相关性研究  

Risk Factor Analysis of the Rupture of Intracranial Aneurysm by CTA Reconstruction with 3D-Slicer Software

作　　者：费佳 段凯[1] FEI Jia;DUAN Kai(Department of Radiology,Beijing Fangshan District Liangxiang Hospital,Beijing 102401,China)

机构地区：[1]北京市房山区良乡医院影像科,北京102401

出　　处：《中国CT和MRI杂志》2023年第3期35-37,共3页Chinese Journal of CT and MRI

摘　　要：目的探讨基于3D-Slicer软件行CTA重建的方法预测颅内动脉瘤破裂的危险因素。方法搜集我院2016.01-2021.06月行CTA检查确诊的颅内动脉瘤200例,用3D-Slicer软件重建头部血管,并测量各项指标。将动脉瘤分为破裂组105例、未破裂组95例。比较各指标在两组之间的差异,行二元Logistic回归分析及ROC曲线确定预测动脉瘤破裂的独立危险因素及诊断效能。结果两组患者年龄、性别均无统计学差异(P>0.05)。动脉瘤形态、部位、最大径、宽度、高度、瘤颈宽度、载瘤动脉平均直径、AR、SR、长宽比、入射角度、动脉瘤表面积、体积在两组间均存在显著统计学差异(P<0.001)。二元Logistic回归分析显示动脉瘤形态不规则、入射角>116.22°是预测动脉瘤破裂的独立危险因素。ROC曲线显示AUC达0.916,当最佳临界值为0.41时,诊断效能好,其灵敏度为81.0%、特异度为89.5%。结论动脉瘤形态不规则、入射角>116.22°是预测动脉瘤破裂的独立危险因素。Objective To predict the risk factors affecting the rupture of intracranial aneurysm by CTA reconstruction with 3D-Slicer software.Methods The 200 cases with intracranial aneurysm from Beijing Fangshan District Liangxiang Hospital during January 2016 to June 2021 were analyzed and reconstructed by 3D-Slicer software,and morphological parameters were measured.This study was divided into 105 cases of rupture group and 95 cases of non-rupture group.The clinical feature and morphological parameters between groups were compered.The binary regression analysis was used to predict the risk factors for ruptured intracranial aneurysm.The ROC curve was used to identify the diagnostic value for predicting ruptured aneurysm.Results There were no statistical difference in age,sex among rupture group and non-rupture group.There were statistically significant differences in aneurysm location,shape,the largest diameter of aneurysm,aneurysm height,aneurysm width,neck width,mean diameter of parent artery,aspect ratio(AR),size ratio(SR),diameter-width ratio,flow angle,surface area and volume between groups.The binary regression analysis results showed irregular shape and flow angle>116.22°were important risk factors in predicting ruptured intracranial aneurysm.The ROC curve displayed higher sensitivity and specificity,respectively 81.0%,89.5%,with an AUC of 0.916,when the cutoff was 0.41.Conclusion The irregular shape and flow angle>116.22°were important risk factors in predicting ruptured intracranial aneurysm.

关 键 词：颅内动脉瘤 3D-Slicer软件 破裂 危险因素 

分 类 号：R445.3[医药卫生—影像医学与核医学] R743.9[医药卫生—诊断学]