CT评估脂肪坏死联合CT严重指数评分对急性胰腺炎严重程度和预后的预测价值  

CT Evaluation of Fat Necrosis Deposits Combined with CT Severity Index in Predicting the Severity and Prognosis of Acute Pancreatitis

作　　者：陈露 付丽媛 许尚文 CHEN Lu;FU Li-yuan;XU Shang-wen(Department of Radiology,the 900th Hospital of the joint logistics support force,Fuzhou 350025,Fujian Province,China)

机构地区：[1]联勤保障部队第九〇〇医院放射诊断科,福建福州350025

出　　处：《中国CT和MRI杂志》2023年第3期119-120,138,共3页Chinese Journal of CT and MRI

基　　金：福建省科技厅对外合作项目(2021I0037)。

摘　　要：目的 探讨CT评估脂肪坏死联合CT严重指数(FND-CTSI)评分对急性胰腺炎(AP)严重程度和预后的预测价值。方法 回顾性分析2021年10月至2022年3月收治的85例AP患者的CT影像学和临床资料,其中SAP31例(SAP组),非SAP54例(非SAP组),比较两组患者CTSI评分和FND-CTSI评分之间的差异。通过受试者工作特征(ROC)曲线分析CTSI和FND-CTSI评分对SAP和死亡的预测价值,并计算曲线下面积(AUC)。结果 SAP组CTSI评分(7.39±1.02比4.76±1.10)和FND-CTSI评分(10.10±2.30比4FND-CTSI评分预测SAP和死亡的AUC及其95%置信区间分别为0.996(95%CI:0.988-1.003)和0.992(95%CI:0.976-1.007),CTSI评分预测SAP和死亡的AUC及其95%置信区间分别为0.959(95%CI:0.920-0.998)和0.856(95%CI:0.701-1.012),FND-CTSI评分预测SAP和死亡的准确性均显著高于CTSI评分(P<0.05)。FND-CTSI评分截断值取75时预测SAP的敏感性和特异性分别为90.3%和100%。FND-CTSI评分截断值取11.5时预测死亡的敏感性和特异性分别为85.7%和94.9%。结论 FND-CTSI评分可以用于对SAP和死亡的预测,且其对SAP和预后的预测价值优于CTSI评分。Objective To explore the predictive value of CT evaluation of fat necrosis combined with CT severity index(FND-CTSI)in the severity and prognosis of acute pancreatitis(AP).Methods The CT imaging and clinical data of 85 patients with AP from October 2021 to March 2022 were analyzed retrospectively,including 31 cases of SAP(SAP group)and 54 cases of non-SAP(non-SAP group).The differences between the two groups were compared.The predictive value of CTSI and FND-CTSI scores for SAP and mortality was analyzed through the receiver operating characteristic(ROC)curve,and the area under the curve(AUC)was calculated.Results The CTSI score(7.39±1.02 vs 4.76±1.10)and FND-CTSI score(10.10±2.30 vs 4.87±1.18)in SAP group were significantly higher than those in non-SAP group(P<0.05).The AUC and its 95%confidence interval of FND-CTSI score in predicting SAP and mortality were 0.996(95%CI:0.988-1.003)and 0.992(95%CI:0.976-1.007),respectively.The AUC and its 95%confidence interval of CTSI score in predicting SAP and mortality were 0.959(95%CI:0.920-0.998)and 0.856(95%CI:0.701-1.012),respectively.The accuracy of fnd-ctsi score in predicting SAP and mortality was significantly higher than that of CTSI score(P<0.05).When the cutoff value of FND-CTSI score is 7.5,the sensitivity and specificity of predicting SAP are 90.3%and 100%respectively.When the cutoff value of FND-CTSI score is 11.5,the sensitivity and specificity of predicting mortality are 85.7%and 94.9%respectively.Conclusion FND-CTSI score can be used to predict SAP and mortality,and its predictive value for SAP and prognosis is better than CTSI score.

关 键 词：急性胰腺炎 电子计算机体层扫描 脂肪坏死 CT严重指数 

分 类 号：R445.3[医药卫生—影像医学与核医学]