腹腔镜全麻术中应用地佐辛对患者术后拔管反应及寒战的影响  

Effets of dezocine used in general anesthesia during laparoscopic surgery of patients on their PostoPerative extubation reaction and chills

作　　者：杨程[1] 朱明慧[1] 朱娟[1] 徐晓红[1] YANG Cheng;ZHU Minghui;ZHU Juan;XU Xiaohong(Jiangsu Prorince Hospilal of Chinese Medicine,Nanjing,Jiangsu Province,210029)

机构地区：[1]江苏省中医院,南京210029

出　　处：《中国计划生育学杂志》2023年第3期537-541,共5页Chinese Journal of Family Planning

摘　　要：目的:分析地佐辛对妇科腹腔镜全麻患者拔管反应、术后寒战发生情况的影响。方法:以2021年1月-2021年12月在本院行全麻腹腔镜手术患者93例,随机分为观察组(n=46)与对照组(n=47),观察组在手术结束前30min内静脉滴注地佐辛0.1mg/kg,对照组以相同方式给予同等量生理盐水。观察两组患者在给药前(T0)、给药后10min(T1)、拔管即刻(T2)、拔管后5min(T3)血流动力学变化及Ramsay镇静评分变化情况,拔管时呛咳、躁动等拔管反应发生情况,手术时间及苏醒时间;采用Wrench评估寒战情况,观察术后不良反应发生率。结果:观察组T1、T2、T3时血流动力学及Ramsay镇静评分均低于对照组,拔管反应发生率(4.4%)低于对照组(19.2%)(P<0.05);两组手术时间及苏醒时间无差异(P>0.05);对照组术后寒战发生率(40.4%)高于观察组(13.0%)(P<0.05),术后24h内不良反应发生率(25.5%)无与观察组(17.4%)无差异(P>0.05)。结论:腹腔镜全麻术中应用地佐辛能够显著降低患者拔管反应及术后寒战发生率,有效稳定患者术中血流动力变化及镇静深度。Obiective:To analyze the efects of dexocine used in general anesthesia during laparoscopic surgery of Patients on their postoperative extubation reaction and chll.Methods:A total of 93 patients who wanted laparoscopic surgery under general anesthesia were selected a the study subjects and were randomly divided into study group(n=46)and control group(n=47)from January 2021 to December 2021.The patients in the study group were given intravenous injection of dezocine 0.1 mg/kg within half an hour before the end of the surgery,while the patients in the control group were given intravenous injection of the same amount of normal saline.The changes of the hemodynamic and Ramsay sedation secore of the patients in the two groups were observed before administration(T0).at 10min after administration(T1),immediately after extubation(T2),and at 5min after extubation(T3).The occurrence of extubation reactions,such as coughing and agitation.the operation time,the awakening time.the chills situation evaluated by Wrench,and the postoperative adverse reactions of the patients in the two groups were observed.Results:The scores of hemodynamics and Ramsay sedation of the patients in the study group at T1,T2,and T3 were significanly lower than those of the patients in the control group.The incidence of extubation reaction(4.4%)of the patients in the study group was significantly lower than that(19.2%)of the patients in the control group(P<0.05).There were no signifiant differences in the operation time and the awakening time of the patients between the two groups(P>0.05).The incidence of postoperative chills(40.4%)of the patients in the control group was significantly higher than that(13.0%)of the patients in the study group(P<0.05).The incidence of adverse reactions within 24 hours after surgery(25.5%)of the patients in the study group was not diferent from that(17.4%)of the patients in the control group(P>0.05).Conclusion:The intraoperative application of dexcine in general anesthesia during laparoscopie surgery of the patients can

关 键 词：腹腔镜手术 全麻 地佐辛 拔管反应 寒战 血流动力学 镇静 

分 类 号：R614[医药卫生—麻醉学]