间接灸联合补肾祛瘀通督丸治疗强直性脊柱炎的疗效观察  

Therapeutic observation of indirect moxibustion combined with Bu Shen Qu Yu Tong Du Wan for ankylosing spondylitis

作　　者：周星宇 王新义[2] 张玉飞 毛丹 喻苗苗 王晓龙 田元生[2] ZHOU Xingyu;WANG Xinyi;ZHANG Yufei;MAO Dan;YU Miaomiao;WANG Xiaolong;TIAN(Yuansheng2.1.Henan University of Chinese Medicine,Zhengzhou 450000,China;The Affiliated Hospital of Henan Academy of Chinese Medicine,Zhengzhou 450004,China)

机构地区：[1]河南中医药大学,郑州450000 [2]河南省中医药研究院附属医院,郑州450004

出　　处：《上海针灸杂志》2023年第3期289-293,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：河南省科技攻关项目(162102310371);河南省中医药科学研究专项课题(2018ZY1020);河南省卫生健康委国家中医临床研究基地科研专项(2021JDZX2134)。

摘　　要：目的观察间接灸联合补肾祛瘀通督丸治疗强直性脊柱炎(ankylosing spondylitis,AS)的临床疗效。方法将90例AS患者随机分为治疗组和西药组,每组45例。治疗组给予任督周天药酒灸联合口服补肾祛瘀通督丸治疗,西药组给予常规西药口服。观察两组治疗前后Bath强直性脊柱炎病情活动指数(Bath ankylosing spondylitis disease activity index,BASDAI)和Bath强直性脊柱炎功能指数(Bath ankylosing spondylitis functional index,BASFI)评分、枕墙距、Schober试验指标(脊柱活动度)、血沉(erythrocyte sedimentation rate,ESR)及血清C反应蛋白(C-reactive protein,CRP)水平变化,并比较两组临床疗效和不良反应发生率。结果治疗后,两组BASDAI评分、BASFI评分、枕墙距、ESR、血清CRP水平均较治疗前降低(P<0.05),脊柱活动度大于治疗前(P<0.05);治疗组以上指标均优于西药组(P<0.05)。治疗组的总有效率为88.9%,明显高于西药组的73.3%(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论间接灸联合补肾祛瘀通督丸治疗AS,可以降低疾病活动度,缓解疼痛程度,提高脊柱功能,降低炎症指标水平,效果优于西药治疗。Objective To observe the clinical efficacy of indirect moxibustion plus Bu Shen Qu Yu Tong Du Wan in treating ankylosing spondylitis(AS).Method Ninety AS patients were randomized into a treatment group and a Western medication group,with 45 cases in each group.The treatment group was given Ren Du Zhou Tian Yao Jiu(indirect moxibustion with medicated wine along the Conception and Governor Vessels)plus oral administration of Bu Shen Qu Yu Tong Du Wan,and the Western medication group was offered the conventional oral Western medication.Before and after treatment,Bath ankylosing spondylitis disease activity index(BASDAI),Bath ankylosing spondylitis functional index(BASFI),occiput-wall distance,Schober’s test(spinal range of motion),erythrocyte sedimentation rate(ESR),and serum C-reactive protein were observed.Clinical efficacy and adverse reaction rate were also compared between the two groups.Result After treatment,the BASDAI score,BASFI score,occiput-wall distance,and ESR and serum CRP levels decreased in the two groups(P<0.05),and the spinal range of motion was enlarged(P<0.05);the treatment group outperformed the Western medication group in comparing the above measures(P<0.05).The total effective rate was 88.9%in the treatment group,notably higher than 73.3%in the Western medication group(P<0.05).There was no significant between-group difference in the adverse reaction rate(P>0.05).Conclusion In the treatment of AS,indirect moxibustion plus Bu Shen Qu Yu Tong Du Wan can reduce the disease activity,reduce pain,enhance spinal function,and down-regulate inflammatory indicator levels,producing more significant efficacy than Western medication treatment.

关 键 词：灸法 穴位贴敷法 间接灸 脊柱炎 强直性 Bath强直性脊柱炎病情活动指数 Bath强直性脊柱炎功能指数 

分 类 号：R246.2[医药卫生—针灸推拿学]