不同铁芯材料对经颅磁刺激电磁场分布的对比研究  

Comparative study on transcranical magnetic stimulation electromagnetic field distribution of different iron core materials

作　　者：孙钰婷 逯迈 SUN Yuting;LU Mai(Key Laboratory of Optoelectronic Technology and Intelligent Control of Ministry of Education,Lanzhou Jiaotong University,Lanzhou 730070,China)

机构地区：[1]兰州交通大学光电技术与智能控制教育部重点实验室,兰州730070

出　　处：《生物医学工程研究》2022年第4期382-390,共9页Journal Of Biomedical Engineering Research

基　　金：国家自然科学基金资助项目(51867014,51567015)。

摘　　要：本研究以电磁感应原理为基础,使用三维有限元仿真软件COMSOL模拟经颅磁刺激过程,并通过在线圈中引入铁芯来增强磁场的刺激强度和深度。为探究影响线圈强度的因素,通过分析硅钢、铁粉芯、高磁通粉芯、铁镍钼合金粉芯、铁氧体五种铁芯材料以及不同材料高度、半径对颅内感应电磁场分布、线圈聚焦性能的影响,得出不同材料的优化参数。结果表明,随铁芯半径与高度增加,线圈刺激强度增强,聚焦能力与刺激深度呈现规律性变化。与空心线圈相比,硅钢材料最高可增强46.2%的磁场强度;高磁通粉芯材料可提高60.6%的电场强度;铁镍钼合金与高磁通粉芯材料的聚焦性能分别提高了9.63%和9.08%;铁芯线圈可以达到优化经颅磁刺激的效果。本研究可为经颅磁刺激线圈的设计提供参考,并辅助临床治疗。We used three-dimensional finite element simulation software COMSOL to simulate the process of transcranial magnetic stimulation based on the electromagnetic induction principle,and enhanced the stimulation depth of the magnetic field by introducing an iron core into the cois.In order to explore the factors which affected the coil strength,the optimization parameters of different materials were obtained by analyzing the influence of silicon steel,iron powder core,high magnetic flux powder core,iron nickel molybdenum alloy powder core and ferrite,as well as the height and radius of different materials,on the distribution of intracranial electromagnetic field and the focusing performance of coil,The results showed that the stimulation intensity of the coil increased with the increase of the radius and height of the iron core,and the focusing ability and stimulation depth changed regularly,the magnetic field strength of silicon steel could be increased by 46.2%,the electric field strength of alloy powder core high flux could be increased by 60.6%compared with the air circular coil.The focusing properties of iron nickel molybdenum alloy powder core and ferrite and the high magnetic flux powder core materials were improved by 9.63%and 9.08%,respectively.The iron core coils could optimize the effect of transcranial magnetic stimulation.This study can provide a reference for transcranial magnetic stimulation coil design,so as to assist clinical treatment.

关 键 词：磁刺激 铁芯参数 聚焦面积 刺激强度 感应电场分布 有限元仿真 

分 类 号：R318.08[医药卫生—生物医学工程] TM153[医药卫生—基础医学]