抗生素对胎膜早破早产合并生殖道感染的治疗效果研究  

Study the therapeutic effect of antibiotics on premature rupture of membranes with reproductive tract infection

作　　者：马旭 MA Xu(Department of Obstetrics and Gynecology,Chaoyang Central Hospital,Chaoyang 122000,China)

机构地区：[1]朝阳市中心医院妇产科,122000

出　　处：《中国实用医药》2023年第4期121-123,共3页China Practical Medicine

摘　　要：目的研究抗生素对胎膜早破早产合并生殖道感染的治疗效果。方法100例胎膜早破早产患者,依照其是否合并生殖道感染分为观察组(合并)和参照组(未合并),每组50例。两组患者均接受宫缩剂、糖皮质激素治疗,观察组在此基础上根据宫颈分泌物检测结果给予抗生素治疗。对比两组的妊娠结局以及新生儿结局。结果观察组产褥感染、产后出血以及绒毛膜羊膜炎发生率分别为8.00%、4.00%、8.00%,与参照组的12.00%、10.00%、10.00%对比差异均无统计学意义(P>0.05)。观察组新生儿体质量为(2.64±0.40)kg、肺炎发生率为12.00%,与参照组的(2.56±0.35)kg、14.00%对比差异无统计学意义(P>0.05)。结论对胎膜早破早产合并生殖道感染患者宫内感染以及胎儿情况进行严密观察,在确定感染致病菌后使用抗生素实行抗感染治疗,能够实现改善妊娠结局的目标,使母婴安全得到有效保障。Objective To study the therapeutic effect of antibiotics on premature rupture of membranes with reproductive tract infection.Methods A total of 100 patients with premature rupture of membranes were divided into observation group(combined with reproductive tract infection)and reference group(not combined with reproductive tract infection)according to whether they were combined with reproductive tract infection,with 50 cases in each group.Patients in both groups received contraction agents and glucocorticoids,and the observation group was given antibiotics based on the results of cervical secretion test.The pregnancy outcomes as well as neonatal outcomes were compared between the two groups.Results The incidence of puerperal infection,postpartum hemorrhage,and chorioamnionitis in the observation group were 8.00%,4.00%,and 8.00%,respectively,and the differences were not statistically significant when compared with 12.00%,10.00%,and 10.00%in the reference group(P>0.05).In the observation group,the neonatal body mass was(2.64±0.40)kg and the incidence of pneumonia was 12.00%,and the differences were not statistically significant when compared with(2.56±0.35)kg and 14.00%in the reference group(P>0.05).Conclusion For patients with premature rupture of membranes and reproductive tract infection,the intrauterine infection and fetal conditions should be closely observed.Antibiotics should be used to carry out anti-infection treatment after identifying pathogenic bacteria,so as to improve the pregnancy outcome and effectively guarantee the safety of mother and infant.

关 键 词：抗生素 胎膜早破早产 生殖道感染 治疗效果 

分 类 号：R714.433[医药卫生—妇产科学] R714.21[医药卫生—临床医学]